A pilot pragmatic trial of a “what matters most”-based intervention targeting intersectional stigma related to being pregnant and living with HIV in Botswana

Abstract We conducted a pilot trial of an intervention targeting intersectional stigma related to being pregnant and living with HIV while promoting capabilities for achieving ‘respected motherhood’ (‘what matters most’) in Botswana. A pragmatic design allocated participants to the intervention (N =...

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Main Authors: Lawrence H. Yang, Evan L. Eschliman, Haitisha Mehta, Supriya Misra, Ohemaa B. Poku, Patlo Entaile, Timothy D. Becker, Tadele Melese, Merrian J. Brooks, Marlene Eisenberg, Melissa A. Stockton, Karen Choe, Danielle Tal, Tingyu Li, Vivian F. Go, Bruce G. Link, Shathani Rampa, Valerie W. Jackson, Gorata D. Manyeagae, Tonya Arscott-Mills, Melody Goodman, Philip R. Opondo, Ari R. Ho-Foster, Michael B. Blank
Format: Article
Language:English
Published: BMC 2022-06-01
Series:AIDS Research and Therapy
Subjects:
Online Access:https://doi.org/10.1186/s12981-022-00454-3
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author Lawrence H. Yang
Evan L. Eschliman
Haitisha Mehta
Supriya Misra
Ohemaa B. Poku
Patlo Entaile
Timothy D. Becker
Tadele Melese
Merrian J. Brooks
Marlene Eisenberg
Melissa A. Stockton
Karen Choe
Danielle Tal
Tingyu Li
Vivian F. Go
Bruce G. Link
Shathani Rampa
Valerie W. Jackson
Gorata D. Manyeagae
Tonya Arscott-Mills
Melody Goodman
Philip R. Opondo
Ari R. Ho-Foster
Michael B. Blank
author_facet Lawrence H. Yang
Evan L. Eschliman
Haitisha Mehta
Supriya Misra
Ohemaa B. Poku
Patlo Entaile
Timothy D. Becker
Tadele Melese
Merrian J. Brooks
Marlene Eisenberg
Melissa A. Stockton
Karen Choe
Danielle Tal
Tingyu Li
Vivian F. Go
Bruce G. Link
Shathani Rampa
Valerie W. Jackson
Gorata D. Manyeagae
Tonya Arscott-Mills
Melody Goodman
Philip R. Opondo
Ari R. Ho-Foster
Michael B. Blank
author_sort Lawrence H. Yang
collection DOAJ
description Abstract We conducted a pilot trial of an intervention targeting intersectional stigma related to being pregnant and living with HIV while promoting capabilities for achieving ‘respected motherhood’ (‘what matters most’) in Botswana. A pragmatic design allocated participants to the intervention (N = 44) group and the treatment-as-usual (N = 15) group. An intent-to-treat, difference-in-difference analysis found the intervention group had significant decreases in HIV stigma (d = − 1.20; 95% CI − 1.99, − 0.39) and depressive symptoms (d = − 1.96; 95% CI − 2.89, − 1.02) from baseline to 4-months postpartum. Some, albeit less pronounced, changes in intersectional stigma were observed, suggesting the importance of structural-level intervention components to reduce intersectional stigma.
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spelling doaj.art-cb961a705ee14879bd20b4a8f51bd8be2022-12-22T02:38:15ZengBMCAIDS Research and Therapy1742-64052022-06-0119111110.1186/s12981-022-00454-3A pilot pragmatic trial of a “what matters most”-based intervention targeting intersectional stigma related to being pregnant and living with HIV in BotswanaLawrence H. Yang0Evan L. Eschliman1Haitisha Mehta2Supriya Misra3Ohemaa B. Poku4Patlo Entaile5Timothy D. Becker6Tadele Melese7Merrian J. Brooks8Marlene Eisenberg9Melissa A. Stockton10Karen Choe11Danielle Tal12Tingyu Li13Vivian F. Go14Bruce G. Link15Shathani Rampa16Valerie W. Jackson17Gorata D. Manyeagae18Tonya Arscott-Mills19Melody Goodman20Philip R. Opondo21Ari R. Ho-Foster22Michael B. Blank23Department of Social and Behavioral Sciences, School of Global Public Health, New York UniversityDepartment of Health, Behavior and Society, Bloomberg School of Public Health, Johns Hopkins UniversityDepartment of Clinical and Counseling Psychology, Teachers College, Columbia UniversityDepartment of Public Health, San Francisco State UniversityDivision of Gender, Sexuality, and Health, HIV Center for Clinical and Behavioral Studies, Columbia University and New York State Psychiatric InstituteBotswana-UPenn PartnershipDepartment of Psychiatry, Icahn School of Medicine at Mount SinaiDepartment of Obstetrics and Gynaecology, Faculty of Medicine, University of BotswanaBotswana-UPenn PartnershipDepartment of Psychiatry, Perelman School of Medicine, University of PennsylvaniaDepartment of Psychiatry, Columbia University Vagelos College of Physicians and Surgeons & New York State Psychiatric InstituteDepartment of Clinical and Counseling Psychology, Teachers College, Columbia UniversityDepartment of Clinical and Counseling Psychology, Teachers College, Columbia UniversityDepartment of Clinical and Counseling Psychology, Teachers College, Columbia UniversityDepartment of Health Behavior, Gillings School of Global Public Health, University of North Carolina at Chapel HillSchool of Public Policy, University of California RiversideDepartment of Psychology, University of BotswanaDepartment of Anesthesia, University of California San FranciscoDepartment of Statistics, Faculty of Social Sciences, University of BotswanaDepartment of Pediatrics and Adolescent Health, Faculty of Medicine, University of BotswanaDepartment of Biostatistics, School of Global Public Health, New York UniversityDepartment of Psychiatry, Faculty of Medicine, University of BotswanaCenter for Global Health, Perelman School of Medicine, University of PennsylvaniaDepartment of Psychiatry, Perelman School of Medicine, University of PennsylvaniaAbstract We conducted a pilot trial of an intervention targeting intersectional stigma related to being pregnant and living with HIV while promoting capabilities for achieving ‘respected motherhood’ (‘what matters most’) in Botswana. A pragmatic design allocated participants to the intervention (N = 44) group and the treatment-as-usual (N = 15) group. An intent-to-treat, difference-in-difference analysis found the intervention group had significant decreases in HIV stigma (d = − 1.20; 95% CI − 1.99, − 0.39) and depressive symptoms (d = − 1.96; 95% CI − 2.89, − 1.02) from baseline to 4-months postpartum. Some, albeit less pronounced, changes in intersectional stigma were observed, suggesting the importance of structural-level intervention components to reduce intersectional stigma.https://doi.org/10.1186/s12981-022-00454-3Intersectional stigmaStigma interventionPregnant women living with HIVCultureBotswana
spellingShingle Lawrence H. Yang
Evan L. Eschliman
Haitisha Mehta
Supriya Misra
Ohemaa B. Poku
Patlo Entaile
Timothy D. Becker
Tadele Melese
Merrian J. Brooks
Marlene Eisenberg
Melissa A. Stockton
Karen Choe
Danielle Tal
Tingyu Li
Vivian F. Go
Bruce G. Link
Shathani Rampa
Valerie W. Jackson
Gorata D. Manyeagae
Tonya Arscott-Mills
Melody Goodman
Philip R. Opondo
Ari R. Ho-Foster
Michael B. Blank
A pilot pragmatic trial of a “what matters most”-based intervention targeting intersectional stigma related to being pregnant and living with HIV in Botswana
AIDS Research and Therapy
Intersectional stigma
Stigma intervention
Pregnant women living with HIV
Culture
Botswana
title A pilot pragmatic trial of a “what matters most”-based intervention targeting intersectional stigma related to being pregnant and living with HIV in Botswana
title_full A pilot pragmatic trial of a “what matters most”-based intervention targeting intersectional stigma related to being pregnant and living with HIV in Botswana
title_fullStr A pilot pragmatic trial of a “what matters most”-based intervention targeting intersectional stigma related to being pregnant and living with HIV in Botswana
title_full_unstemmed A pilot pragmatic trial of a “what matters most”-based intervention targeting intersectional stigma related to being pregnant and living with HIV in Botswana
title_short A pilot pragmatic trial of a “what matters most”-based intervention targeting intersectional stigma related to being pregnant and living with HIV in Botswana
title_sort pilot pragmatic trial of a what matters most based intervention targeting intersectional stigma related to being pregnant and living with hiv in botswana
topic Intersectional stigma
Stigma intervention
Pregnant women living with HIV
Culture
Botswana
url https://doi.org/10.1186/s12981-022-00454-3
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