Effect of Melatonin Plus Zinc Supplementation on Fatigue Perception in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial

Effect of Melatonin Plus Zinc Supplementation on Fatigue Perception in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial

Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a complex, multisystem, and profoundly debilitating condition, probably of multifactorial etiology. No effective approved drugs are currently available for its treatment. Several studies have proposed symptomatic treatment with melatonin...

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Bibliographic Details
Main Authors: Jesús Castro-Marrero, Maria-Cleofé Zaragozá, Irene López-Vílchez, José Luis Galmés, Begoña Cordobilla, Sara Maurel, Joan Carles Domingo, José Alegre-Martín
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Antioxidants
Subjects:
chronic fatigue syndrome
fatigue
myalgic encephalomyelitis
melatonin
quality of life
sleep quality
Online Access:https://www.mdpi.com/2076-3921/10/7/1010

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