NBCe2 (Slc4a5) Is Expressed in the Renal Connecting Tubules and Cortical Collecting Ducts and Mediates Base Extrusion

NBCe2 (Slc4a5) Is Expressed in the Renal Connecting Tubules and Cortical Collecting Ducts and Mediates Base Extrusion

Arterial hypertension, is a common disorder with multiple and variable etiologies. Single nucleotide polymorphism analyses have detected an association between variants in the gene encoding the electrogenic Na+:HCO3– cotransporter NBCe2 (Slc4a5), and salt-sensitive hypertension. Mice with genetic de...

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Bibliographic Details
Main Authors: Dagne Barbuskaite, Fredrik D. Pedersen, Henriette L. Christensen, Laura Ø. Johnsen, Jeppe Praetorius, Helle H. Damkier
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Physiology
Subjects:
NBCe2
kidney
blood pressure
Slc4a5
hypertension
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2020.00560/full

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