PROMIS-9 UE physical function demonstrates moderate responsiveness for patients following upper limb prosthesis intervention

Abstract Background Upper extremity physical function is an essential health domain in the rehabilitation care for patients with upper limb amputation or absence. The PROMIS-9 UE Physical Function short form is a recently established instrument designed for individuals with upper limb amputation or...

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Main Authors: Todd J. Castleberry, Dwiesha L. England, Bretta L. Fylstra, Phillip M. Stevens, Amy E. Todd, Stephen A. Mandacina, Shane R. Wurdeman
Format: Article
Language:English
Published: SpringerOpen 2025-02-01
Series:Journal of Patient-Reported Outcomes
Subjects:
Online Access:https://doi.org/10.1186/s41687-025-00843-y
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author Todd J. Castleberry
Dwiesha L. England
Bretta L. Fylstra
Phillip M. Stevens
Amy E. Todd
Stephen A. Mandacina
Shane R. Wurdeman
author_facet Todd J. Castleberry
Dwiesha L. England
Bretta L. Fylstra
Phillip M. Stevens
Amy E. Todd
Stephen A. Mandacina
Shane R. Wurdeman
author_sort Todd J. Castleberry
collection DOAJ
description Abstract Background Upper extremity physical function is an essential health domain in the rehabilitation care for patients with upper limb amputation or absence. The PROMIS-9 UE Physical Function short form is a recently established instrument designed for individuals with upper limb amputation or absence. The instrument’s responsiveness to changes after receiving a prosthesis has not been investigated. The current study aimed to evaluate the ability of the PROMIS-9 UE to detect changes in bimanual (two-handed) functional capacity after patients’ receipt of a prosthesis. Methodology A retrospective chart review was conducted on the longitudinal PROMIS-9 UE outcome measure scores completed between April 2016 and February 2024. Participants included individuals with an outcome collected before and after prosthesis receipt. Results The final sample size included 124 individuals (91 male, 33 female; 43.4 ± 15.0 years old, 34.4 ± 103.0 months since amputation, and 62.9% injury etiology). Analyses found significant improvement across all patients in the PROMIS-9 UE scores from baseline to post prosthesis intervention (baseline: 25.3 ± 8.6, post: 29.5 ± 9.6; p < 0.001). The PROMIS-9 UE demonstrated a moderate responsiveness (Standardized Response Mean = 0.6) to prosthetic intervention. This was a directional change consistent with subjective patient reports of increased functionality. Furthermore, findings from the linear mixed model demonstrated significant responsiveness for the PROMIS-9 UE instrument to detect post-intervention changes after controlling for potential confounding effects (p < 0.001). Conclusions These findings suggest the PROMIS-9 UE Physical Function instrument demonstrates moderate clinical utility in capturing patient progress following upper limb prosthesis intervention.
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spelling doaj.art-cb9a902527fe4e2ba1e884da541784382025-02-16T12:33:06ZengSpringerOpenJournal of Patient-Reported Outcomes2509-80202025-02-01911610.1186/s41687-025-00843-yPROMIS-9 UE physical function demonstrates moderate responsiveness for patients following upper limb prosthesis interventionTodd J. Castleberry0Dwiesha L. England1Bretta L. Fylstra2Phillip M. Stevens3Amy E. Todd4Stephen A. Mandacina5Shane R. Wurdeman6Hanger Institute for Clinical Research and EducationHanger Institute for Clinical Research and EducationHanger Institute for Clinical Research and EducationHanger Institute for Clinical Research and EducationUpper Limb Program, Hanger ClinicUpper Limb Program, Hanger ClinicHanger Institute for Clinical Research and EducationAbstract Background Upper extremity physical function is an essential health domain in the rehabilitation care for patients with upper limb amputation or absence. The PROMIS-9 UE Physical Function short form is a recently established instrument designed for individuals with upper limb amputation or absence. The instrument’s responsiveness to changes after receiving a prosthesis has not been investigated. The current study aimed to evaluate the ability of the PROMIS-9 UE to detect changes in bimanual (two-handed) functional capacity after patients’ receipt of a prosthesis. Methodology A retrospective chart review was conducted on the longitudinal PROMIS-9 UE outcome measure scores completed between April 2016 and February 2024. Participants included individuals with an outcome collected before and after prosthesis receipt. Results The final sample size included 124 individuals (91 male, 33 female; 43.4 ± 15.0 years old, 34.4 ± 103.0 months since amputation, and 62.9% injury etiology). Analyses found significant improvement across all patients in the PROMIS-9 UE scores from baseline to post prosthesis intervention (baseline: 25.3 ± 8.6, post: 29.5 ± 9.6; p < 0.001). The PROMIS-9 UE demonstrated a moderate responsiveness (Standardized Response Mean = 0.6) to prosthetic intervention. This was a directional change consistent with subjective patient reports of increased functionality. Furthermore, findings from the linear mixed model demonstrated significant responsiveness for the PROMIS-9 UE instrument to detect post-intervention changes after controlling for potential confounding effects (p < 0.001). Conclusions These findings suggest the PROMIS-9 UE Physical Function instrument demonstrates moderate clinical utility in capturing patient progress following upper limb prosthesis intervention.https://doi.org/10.1186/s41687-025-00843-yUpper-limb prosthesisPatient-reported outcomesPhysical functionProsthesis receipt
spellingShingle Todd J. Castleberry
Dwiesha L. England
Bretta L. Fylstra
Phillip M. Stevens
Amy E. Todd
Stephen A. Mandacina
Shane R. Wurdeman
PROMIS-9 UE physical function demonstrates moderate responsiveness for patients following upper limb prosthesis intervention
Journal of Patient-Reported Outcomes
Upper-limb prosthesis
Patient-reported outcomes
Physical function
Prosthesis receipt
title PROMIS-9 UE physical function demonstrates moderate responsiveness for patients following upper limb prosthesis intervention
title_full PROMIS-9 UE physical function demonstrates moderate responsiveness for patients following upper limb prosthesis intervention
title_fullStr PROMIS-9 UE physical function demonstrates moderate responsiveness for patients following upper limb prosthesis intervention
title_full_unstemmed PROMIS-9 UE physical function demonstrates moderate responsiveness for patients following upper limb prosthesis intervention
title_short PROMIS-9 UE physical function demonstrates moderate responsiveness for patients following upper limb prosthesis intervention
title_sort promis 9 ue physical function demonstrates moderate responsiveness for patients following upper limb prosthesis intervention
topic Upper-limb prosthesis
Patient-reported outcomes
Physical function
Prosthesis receipt
url https://doi.org/10.1186/s41687-025-00843-y
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