A SUMO E3 ligase promotes long non-coding RNA transcription to regulate small RNA-directed DNA elimination

A SUMO E3 ligase promotes long non-coding RNA transcription to regulate small RNA-directed DNA elimination

Small RNAs target their complementary chromatin regions for gene silencing through nascent long non-coding RNAs (lncRNAs). In the ciliated protozoan Tetrahymena, the interaction between Piwi-associated small RNAs (scnRNAs) and the nascent lncRNA transcripts from the somatic genome has been proposed...

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Bibliographic Details
Main Authors: Salman Shehzada, Tomoko Noto, Julie Saksouk, Kazufumi Mochizuki
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-01-01
Series:eLife
Subjects:
long noncoding RNA
small RNA
epigenetics
SUMO
Tetrahymena
programmed DNA elimination
Online Access:https://elifesciences.org/articles/95337

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