Terpenes extracted from marine sponges with antioxidant activity: a systematic review
Abstract Marine biodiversity has emerged as a very promising resource of bioactive compounds and secondary metabolites from different sea organisms. The sponge’s secondary metabolites demonstrated various bioactivities and potential pharmacological properties. This systematic review of the literatur...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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SpringerOpen
2023-08-01
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| Series: | Natural Products and Bioprospecting |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/s13659-023-00387-y |
| _version_ | 1797451073028358144 |
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| author | Cintia Cristina Santi Martignago Beatriz Soares-Silva Julia Risso Parisi Lais Caroline Souza e Silva Renata Neves Granito Alessandra Mussi Ribeiro Ana Cláudia Muniz Renno Lorena Ramos Freitas de Sousa Anna Caroline Campos Aguiar |
| author_facet | Cintia Cristina Santi Martignago Beatriz Soares-Silva Julia Risso Parisi Lais Caroline Souza e Silva Renata Neves Granito Alessandra Mussi Ribeiro Ana Cláudia Muniz Renno Lorena Ramos Freitas de Sousa Anna Caroline Campos Aguiar |
| author_sort | Cintia Cristina Santi Martignago |
| collection | DOAJ |
| description | Abstract Marine biodiversity has emerged as a very promising resource of bioactive compounds and secondary metabolites from different sea organisms. The sponge’s secondary metabolites demonstrated various bioactivities and potential pharmacological properties. This systematic review of the literature focuses on the advances achieved in the antioxidant potential of marine sponges in vitro. The review was performed in accordance with PRISMA guidelines. The main inclusion criterion for analysis was articles with identification of compounds from terpene classes that demonstrate antioxidant activity in vitro. Searching in three different databases, two hundred articles were selected. After screening abstracts, titles and evaluating for eligibility of manuscripts 14 articles were included. The most performed analyzes to detect antioxidant activity were scavenging activity 2,2-diphenyl-1-picrylhydrazyl (DPPH) and measurement of intracellular reactive oxygen species (ROS). It was possible to identify 17 compounds of the terpene class with pronounced antioxidant activity in vitro. Scientific evidence of the studies included in this review was accessed by the GRADE analysis. Terpenes play an important ecological role, moreover these molecules have a pharmaceutical and industrial application. Graphical Abstract |
| first_indexed | 2024-03-09T14:49:41Z |
| format | Article |
| id | doaj.art-cba454273c3648e994a341077aeeeff0 |
| institution | Directory Open Access Journal |
| issn | 2192-2195 2192-2209 |
| language | English |
| last_indexed | 2024-03-09T14:49:41Z |
| publishDate | 2023-08-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Natural Products and Bioprospecting |
| spelling | doaj.art-cba454273c3648e994a341077aeeeff02023-11-26T14:34:17ZengSpringerOpenNatural Products and Bioprospecting2192-21952192-22092023-08-0113111210.1007/s13659-023-00387-yTerpenes extracted from marine sponges with antioxidant activity: a systematic reviewCintia Cristina Santi Martignago0Beatriz Soares-Silva1Julia Risso Parisi2Lais Caroline Souza e Silva3Renata Neves Granito4Alessandra Mussi Ribeiro5Ana Cláudia Muniz Renno6Lorena Ramos Freitas de Sousa7Anna Caroline Campos Aguiar8Departamento de Biociências, Universidade Federal de São Paulo (UNIFESP)Departamento de Biociências, Universidade Federal de São Paulo (UNIFESP)Departamento de Biociências, Universidade Federal de São Paulo (UNIFESP)Departamento de Biociências, Universidade Federal de São Paulo (UNIFESP)Departamento de Biociências, Universidade Federal de São Paulo (UNIFESP)Departamento de Biociências, Universidade Federal de São Paulo (UNIFESP)Departamento de Biociências, Universidade Federal de São Paulo (UNIFESP)Institute of Chemistry, Federal University of Catalão (UFCAT)Departamento de Biociências, Universidade Federal de São Paulo (UNIFESP)Abstract Marine biodiversity has emerged as a very promising resource of bioactive compounds and secondary metabolites from different sea organisms. The sponge’s secondary metabolites demonstrated various bioactivities and potential pharmacological properties. This systematic review of the literature focuses on the advances achieved in the antioxidant potential of marine sponges in vitro. The review was performed in accordance with PRISMA guidelines. The main inclusion criterion for analysis was articles with identification of compounds from terpene classes that demonstrate antioxidant activity in vitro. Searching in three different databases, two hundred articles were selected. After screening abstracts, titles and evaluating for eligibility of manuscripts 14 articles were included. The most performed analyzes to detect antioxidant activity were scavenging activity 2,2-diphenyl-1-picrylhydrazyl (DPPH) and measurement of intracellular reactive oxygen species (ROS). It was possible to identify 17 compounds of the terpene class with pronounced antioxidant activity in vitro. Scientific evidence of the studies included in this review was accessed by the GRADE analysis. Terpenes play an important ecological role, moreover these molecules have a pharmaceutical and industrial application. Graphical Abstracthttps://doi.org/10.1007/s13659-023-00387-yAntioxidantMarine drugsSpongeFree radical |
| spellingShingle | Cintia Cristina Santi Martignago Beatriz Soares-Silva Julia Risso Parisi Lais Caroline Souza e Silva Renata Neves Granito Alessandra Mussi Ribeiro Ana Cláudia Muniz Renno Lorena Ramos Freitas de Sousa Anna Caroline Campos Aguiar Terpenes extracted from marine sponges with antioxidant activity: a systematic review Natural Products and Bioprospecting Antioxidant Marine drugs Sponge Free radical |
| title | Terpenes extracted from marine sponges with antioxidant activity: a systematic review |
| title_full | Terpenes extracted from marine sponges with antioxidant activity: a systematic review |
| title_fullStr | Terpenes extracted from marine sponges with antioxidant activity: a systematic review |
| title_full_unstemmed | Terpenes extracted from marine sponges with antioxidant activity: a systematic review |
| title_short | Terpenes extracted from marine sponges with antioxidant activity: a systematic review |
| title_sort | terpenes extracted from marine sponges with antioxidant activity a systematic review |
| topic | Antioxidant Marine drugs Sponge Free radical |
| url | https://doi.org/10.1007/s13659-023-00387-y |
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