Polyploidy of semi-cloned embryos generated from parthenogenetic haploid embryonic stem cells
In mammals, the fusion of two gametes, an oocyte and a spermatozoon, during fertilization forms a totipotent zygote. There has been no reported case of adult mammal development by natural parthenogenesis, in which embryos develop from unfertilized oocytes. The genome and epigenetic information of ha...
Main Authors: | Eishi Aizawa, Charles-Etienne Dumeau, Remo Freimann, Giulio Di Minin, Anton Wutz, Jon Schoorlemmer |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2020-01-01
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Series: | PLoS ONE |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7482839/?tool=EBI |
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