What Came First, Mania or Depression? Polarity at Onset in Bipolar I and II: Temperament and Clinical Course

What Came First, Mania or Depression? Polarity at Onset in Bipolar I and II: Temperament and Clinical Course

(1) Background: Bipolar disorder (BD) is divided into type I (BD-I) and type II (BD-II). Polarity at onset (PO) is a proposal to specify the clinical course of BD, based on the type of the first episode at disorder onset—depressive (D-PO) or manic (M-PO). At the same time, affective temperaments rep...

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Bibliographic Details
Main Authors: Delfina Janiri, Alessio Simonetti, Lorenzo Moccia, Daniele Hirsch, Silvia Montanari, Marianna Mazza, Marco Di Nicola, Georgios D. Kotzalidis, Gabriele Sani
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Brain Sciences
Subjects:
bipolar disorder
polarity at onset
affective temperaments
manic/hypomanic polarity
depressive polarity
Online Access:https://www.mdpi.com/2076-3425/14/1/17

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