Vesiculation of Red Blood Cells in the Blood Bank: A Multi-Omics Approach towards Identification of Causes and Consequences

Vesiculation of Red Blood Cells in the Blood Bank: A Multi-Omics Approach towards Identification of Causes and Consequences

Microvesicle generation is an integral part of the aging process of red blood cells in vivo and in vitro. Extensive vesiculation impairs function and survival of red blood cells after transfusion, and microvesicles contribute to transfusion reactions. The triggers and mechanisms of microvesicle gene...

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Bibliographic Details
Main Authors: Joames K. Freitas Leal, Edwin Lasonder, Vikram Sharma, Jürgen Schiller, Giuseppina Fanelli, Sara Rinalducci, Roland Brock, Giel Bosman
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Proteomes
Subjects:
red blood cell
vesicles
proteomics
lipidomics
metabolomics
storage
Online Access:https://www.mdpi.com/2227-7382/8/2/6

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