The Emerging Importance of Mitochondria in White Adipocytes: Neither Last nor Least
The growing recognition of mitochondria’s crucial role in the regulation of white adipose tissue remodeling and energy balance underscores its significance. The marked metabolic diversity of mitochondria provides the molecular and cellular foundation for enabling adipose tissue plasticity in respons...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Korean Endocrine Society
2023-10-01
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| Series: | Endocrinology and Metabolism |
| Subjects: | |
| Online Access: | http://www.e-enm.org/upload/pdf/enm-2023-1813.pdf |
| _version_ | 1797650437844762624 |
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| author | Juan Cai Fenfen Wang Mengle Shao |
| author_facet | Juan Cai Fenfen Wang Mengle Shao |
| author_sort | Juan Cai |
| collection | DOAJ |
| description | The growing recognition of mitochondria’s crucial role in the regulation of white adipose tissue remodeling and energy balance underscores its significance. The marked metabolic diversity of mitochondria provides the molecular and cellular foundation for enabling adipose tissue plasticity in response to various metabolic cues. Effective control of mitochondrial function at the cellular level, not only in thermogenic brown and beige adipocytes but also in energy-storing white adipocytes, exerts a profound influence on adipose homeostasis. Furthermore, mitochondria play a pivotal role in intercellular communication within adipose tissue via production of metabolites with signaling properties. A more comprehensive understanding of mitochondrial regulation within white adipocytes will empower the development of targeted and efficacious strategies to enhance adipose function, leading to advancements in overall metabolic health. |
| first_indexed | 2024-03-11T16:00:22Z |
| format | Article |
| id | doaj.art-cbaad73162764955b0e8e701738b9dd3 |
| institution | Directory Open Access Journal |
| issn | 2093-596X 2093-5978 |
| language | English |
| last_indexed | 2024-03-11T16:00:22Z |
| publishDate | 2023-10-01 |
| publisher | Korean Endocrine Society |
| record_format | Article |
| series | Endocrinology and Metabolism |
| spelling | doaj.art-cbaad73162764955b0e8e701738b9dd32023-10-25T07:28:35ZengKorean Endocrine SocietyEndocrinology and Metabolism2093-596X2093-59782023-10-0138549350310.3803/EnM.2023.18132423The Emerging Importance of Mitochondria in White Adipocytes: Neither Last nor LeastJuan Cai0Fenfen Wang1Mengle Shao2 CAS Key Laboratory of Molecular Virology and Immunology, The Center for Microbes, Development and Health, Shanghai Institute of Immunity and Infection, Chinese Academy of Sciences, Shanghai, China Department of Anesthesiology, Critical Care and Pain Medicine, Center for Perioperative Medicine, McGovern Medical School, UT Health Science Center at Houston, Houston, TX, USA CAS Key Laboratory of Molecular Virology and Immunology, The Center for Microbes, Development and Health, Shanghai Institute of Immunity and Infection, Chinese Academy of Sciences, Shanghai, ChinaThe growing recognition of mitochondria’s crucial role in the regulation of white adipose tissue remodeling and energy balance underscores its significance. The marked metabolic diversity of mitochondria provides the molecular and cellular foundation for enabling adipose tissue plasticity in response to various metabolic cues. Effective control of mitochondrial function at the cellular level, not only in thermogenic brown and beige adipocytes but also in energy-storing white adipocytes, exerts a profound influence on adipose homeostasis. Furthermore, mitochondria play a pivotal role in intercellular communication within adipose tissue via production of metabolites with signaling properties. A more comprehensive understanding of mitochondrial regulation within white adipocytes will empower the development of targeted and efficacious strategies to enhance adipose function, leading to advancements in overall metabolic health.http://www.e-enm.org/upload/pdf/enm-2023-1813.pdfwhite adipocytemitochondriaadipose tissue remodelingmetabolic healthsignaling metabolite |
| spellingShingle | Juan Cai Fenfen Wang Mengle Shao The Emerging Importance of Mitochondria in White Adipocytes: Neither Last nor Least Endocrinology and Metabolism white adipocyte mitochondria adipose tissue remodeling metabolic health signaling metabolite |
| title | The Emerging Importance of Mitochondria in White Adipocytes: Neither Last nor Least |
| title_full | The Emerging Importance of Mitochondria in White Adipocytes: Neither Last nor Least |
| title_fullStr | The Emerging Importance of Mitochondria in White Adipocytes: Neither Last nor Least |
| title_full_unstemmed | The Emerging Importance of Mitochondria in White Adipocytes: Neither Last nor Least |
| title_short | The Emerging Importance of Mitochondria in White Adipocytes: Neither Last nor Least |
| title_sort | emerging importance of mitochondria in white adipocytes neither last nor least |
| topic | white adipocyte mitochondria adipose tissue remodeling metabolic health signaling metabolite |
| url | http://www.e-enm.org/upload/pdf/enm-2023-1813.pdf |
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