Computational identification of potential inhibitors targeting cdk1 in colorectal cancer

Computational identification of potential inhibitors targeting cdk1 in colorectal cancer

Introduction: Despite improved treatment options, colorectal cancer (CRC) remains a huge public health concern with a significant impact on affected individuals. Cell cycle dysregulation and overexpression of certain regulators and checkpoint activators are important recurring events in the progress...

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Bibliographic Details
Main Authors:	Uchechukwu C. Ogbodo, Ojochenemi A. Enejoh, Chinelo H. Okonkwo, Pranavathiyani Gnanasekar, Pauline W. Gachanja, Shamim Osata, Halimat C. Atanda, Emmanuel A. Iwuchukwu, Ikechukwu Achilonu, Olaitan I. Awe
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-11-01
Series:	Frontiers in Chemistry
Subjects:	colorectal cancer cyclin-dependent kinase 1 inhibitors natural compounds molecular dynamics simulation
Online Access:	https://www.frontiersin.org/articles/10.3389/fchem.2023.1264808/full

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