The Role of Catechins in Regulating Diabetes: An Update Review
Catechins are key functional components in tea and have many health benefits, including relieving diabetes. Glucose is necessary for maintaining life. However, when the glucose in the serum exceeds the threshold, it will lead to hyperglycemia. Hyperglycemia is mainly caused by insufficient insulin s...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-11-01
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| Series: | Nutrients |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2072-6643/14/21/4681 |
| _version_ | 1797466926318878720 |
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| author | Lianghua Wen Dan Wu Xindong Tan Meiqi Zhong Jiabao Xing Wei Li Dan Li Fanrong Cao |
| author_facet | Lianghua Wen Dan Wu Xindong Tan Meiqi Zhong Jiabao Xing Wei Li Dan Li Fanrong Cao |
| author_sort | Lianghua Wen |
| collection | DOAJ |
| description | Catechins are key functional components in tea and have many health benefits, including relieving diabetes. Glucose is necessary for maintaining life. However, when the glucose in the serum exceeds the threshold, it will lead to hyperglycemia. Hyperglycemia is mainly caused by insufficient insulin secretion or insulin resistance. Persistent hyperglycemia can cause various disorders, including retinopathy, nephropathy, neurodegenerative diseases, cardiovascular disease, and diabetes. In this paper, we summarize the research on the underlying mechanisms of catechins in regulating diabetes and elaborate on the mechanisms of catechins in alleviating hyperglycemia by improving insulin resistance, alleviating oxidative stress, regulating mitochondrial function, alleviating endoplasmic reticulum stress, producing anti-inflammatory effects, reducing blood sugar source, and regulating intestinal function. This review will provide scientific direction for future research on catechin alleviating diabetes. |
| first_indexed | 2024-03-09T18:46:22Z |
| format | Article |
| id | doaj.art-cbb892c8535d4c9dade4abeb3e225ba0 |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-09T18:46:22Z |
| publishDate | 2022-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-cbb892c8535d4c9dade4abeb3e225ba02023-11-24T06:15:33ZengMDPI AGNutrients2072-66432022-11-011421468110.3390/nu14214681The Role of Catechins in Regulating Diabetes: An Update ReviewLianghua Wen0Dan Wu1Xindong Tan2Meiqi Zhong3Jiabao Xing4Wei Li5Dan Li6Fanrong Cao7College of Horticulture, South China Agricultural University, Guangzhou 510640, ChinaCollege of Horticulture, South China Agricultural University, Guangzhou 510640, ChinaCollege of Horticulture, South China Agricultural University, Guangzhou 510640, ChinaCollege of Horticulture, South China Agricultural University, Guangzhou 510640, ChinaCollege of Horticulture, South China Agricultural University, Guangzhou 510640, ChinaCollege of Horticulture, South China Agricultural University, Guangzhou 510640, ChinaCollege of Horticulture, South China Agricultural University, Guangzhou 510640, ChinaCollege of Horticulture, South China Agricultural University, Guangzhou 510640, ChinaCatechins are key functional components in tea and have many health benefits, including relieving diabetes. Glucose is necessary for maintaining life. However, when the glucose in the serum exceeds the threshold, it will lead to hyperglycemia. Hyperglycemia is mainly caused by insufficient insulin secretion or insulin resistance. Persistent hyperglycemia can cause various disorders, including retinopathy, nephropathy, neurodegenerative diseases, cardiovascular disease, and diabetes. In this paper, we summarize the research on the underlying mechanisms of catechins in regulating diabetes and elaborate on the mechanisms of catechins in alleviating hyperglycemia by improving insulin resistance, alleviating oxidative stress, regulating mitochondrial function, alleviating endoplasmic reticulum stress, producing anti-inflammatory effects, reducing blood sugar source, and regulating intestinal function. This review will provide scientific direction for future research on catechin alleviating diabetes.https://www.mdpi.com/2072-6643/14/21/4681teahyperglycemiainsulin resistanceoxidative stressmitochondrial damagegut |
| spellingShingle | Lianghua Wen Dan Wu Xindong Tan Meiqi Zhong Jiabao Xing Wei Li Dan Li Fanrong Cao The Role of Catechins in Regulating Diabetes: An Update Review Nutrients tea hyperglycemia insulin resistance oxidative stress mitochondrial damage gut |
| title | The Role of Catechins in Regulating Diabetes: An Update Review |
| title_full | The Role of Catechins in Regulating Diabetes: An Update Review |
| title_fullStr | The Role of Catechins in Regulating Diabetes: An Update Review |
| title_full_unstemmed | The Role of Catechins in Regulating Diabetes: An Update Review |
| title_short | The Role of Catechins in Regulating Diabetes: An Update Review |
| title_sort | role of catechins in regulating diabetes an update review |
| topic | tea hyperglycemia insulin resistance oxidative stress mitochondrial damage gut |
| url | https://www.mdpi.com/2072-6643/14/21/4681 |
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