Osteoarticular tuberculosis in Central India: Changing epidemiological profile and emerging challenges
Background: Osteoarticular tuberculosis (OATB) is a form of extrapulmonary tuberculosis (TB) affecting bones and joints. There is a paucity of data on skeletal TB epidemiology in the annual TB reports and current literature. Many atypical presentations of the disease have also emerged. This necessit...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2023-01-01
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| Series: | International Journal of Mycobacteriology |
| Subjects: | |
| Online Access: | http://www.ijmyco.org/article.asp?issn=2212-5531;year=2023;volume=12;issue=1;spage=28;epage=32;aulast=Kori |
| _version_ | 1797866528181321728 |
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| author | Vivek Kumar Kori Deepanshu Bandil Mohit Asthana Deepak Singh Maravi |
| author_facet | Vivek Kumar Kori Deepanshu Bandil Mohit Asthana Deepak Singh Maravi |
| author_sort | Vivek Kumar Kori |
| collection | DOAJ |
| description | Background: Osteoarticular tuberculosis (OATB) is a form of extrapulmonary tuberculosis (TB) affecting bones and joints. There is a paucity of data on skeletal TB epidemiology in the annual TB reports and current literature. Many atypical presentations of the disease have also emerged. This necessitates periodic observation of the epidemiological profile of OATB. The aim of this study is to analyze the prevailing epidemiological trends of OATB in Central India. Methods: The 5-year ambispective observational study was conducted at the department of orthopedics of a tertiary care center in Central India. Records of patients diagnosed with OATB from January 2017 to December 2021 were analyzed for demographic factors, site of lesion, comorbidities (pulmonary TB, human immunodeficiency virus, and diabetes), etc., Chi-square test for linear trend was used to determine whether a linear trend exists in the number of diagnosed cases. Results: Two hundred and ten skeletal TB lesions were found in 208 patients included in the study. OATB was highly reported in young adults and females. Spinal lesions were three times more common than extraspinal OATB lesions. The lumbar spine was the most affected region. Hip was the most common extraspinal site. Unusual sites such as sternoclavicular joint and ischial tuberosity were also involved. Conclusion: The burden of OATB is increasing, especially spinal TB. The involvement of atypical sites insists on strong clinical suspicion for early diagnosis. The practice of empirical antitubercular chemotherapy needs to be reviewed considering the risk of drug resistance. |
| first_indexed | 2024-04-09T23:25:34Z |
| format | Article |
| id | doaj.art-cbb9a92ab4bd4929baec72c54483ad5d |
| institution | Directory Open Access Journal |
| issn | 2212-5531 2212-554X |
| language | English |
| last_indexed | 2024-04-09T23:25:34Z |
| publishDate | 2023-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | International Journal of Mycobacteriology |
| spelling | doaj.art-cbb9a92ab4bd4929baec72c54483ad5d2023-03-21T11:07:45ZengWolters Kluwer Medknow PublicationsInternational Journal of Mycobacteriology2212-55312212-554X2023-01-01121283210.4103/ijmy.ijmy_233_22Osteoarticular tuberculosis in Central India: Changing epidemiological profile and emerging challengesVivek Kumar KoriDeepanshu BandilMohit AsthanaDeepak Singh MaraviBackground: Osteoarticular tuberculosis (OATB) is a form of extrapulmonary tuberculosis (TB) affecting bones and joints. There is a paucity of data on skeletal TB epidemiology in the annual TB reports and current literature. Many atypical presentations of the disease have also emerged. This necessitates periodic observation of the epidemiological profile of OATB. The aim of this study is to analyze the prevailing epidemiological trends of OATB in Central India. Methods: The 5-year ambispective observational study was conducted at the department of orthopedics of a tertiary care center in Central India. Records of patients diagnosed with OATB from January 2017 to December 2021 were analyzed for demographic factors, site of lesion, comorbidities (pulmonary TB, human immunodeficiency virus, and diabetes), etc., Chi-square test for linear trend was used to determine whether a linear trend exists in the number of diagnosed cases. Results: Two hundred and ten skeletal TB lesions were found in 208 patients included in the study. OATB was highly reported in young adults and females. Spinal lesions were three times more common than extraspinal OATB lesions. The lumbar spine was the most affected region. Hip was the most common extraspinal site. Unusual sites such as sternoclavicular joint and ischial tuberosity were also involved. Conclusion: The burden of OATB is increasing, especially spinal TB. The involvement of atypical sites insists on strong clinical suspicion for early diagnosis. The practice of empirical antitubercular chemotherapy needs to be reviewed considering the risk of drug resistance.http://www.ijmyco.org/article.asp?issn=2212-5531;year=2023;volume=12;issue=1;spage=28;epage=32;aulast=Koriepidemiologyextrapulmonaryextraspinalosteoarticularspinaltuberculosis |
| spellingShingle | Vivek Kumar Kori Deepanshu Bandil Mohit Asthana Deepak Singh Maravi Osteoarticular tuberculosis in Central India: Changing epidemiological profile and emerging challenges International Journal of Mycobacteriology epidemiology extrapulmonary extraspinal osteoarticular spinal tuberculosis |
| title | Osteoarticular tuberculosis in Central India: Changing epidemiological profile and emerging challenges |
| title_full | Osteoarticular tuberculosis in Central India: Changing epidemiological profile and emerging challenges |
| title_fullStr | Osteoarticular tuberculosis in Central India: Changing epidemiological profile and emerging challenges |
| title_full_unstemmed | Osteoarticular tuberculosis in Central India: Changing epidemiological profile and emerging challenges |
| title_short | Osteoarticular tuberculosis in Central India: Changing epidemiological profile and emerging challenges |
| title_sort | osteoarticular tuberculosis in central india changing epidemiological profile and emerging challenges |
| topic | epidemiology extrapulmonary extraspinal osteoarticular spinal tuberculosis |
| url | http://www.ijmyco.org/article.asp?issn=2212-5531;year=2023;volume=12;issue=1;spage=28;epage=32;aulast=Kori |
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