Safety evaluation of the food enzyme phytepsin from Cynara cardunculus L.

Abstract The food enzyme phytepsin (EC 3.4.23.40) is extracted from the pistils of cardoon (Cynara cardunculus L.) by QUALIFICA/oriGIn PORTUGAL. It is intended to be used in milk processing for cheese production. As no concerns arose from the source of the food enzyme, from its manufacture, and base...

Full description

Bibliographic Details
Main Authors: EFSA Panel on Food Contact Materials; Enzymes and Processing Aids (CEP), Claude Lambré, José Manuel Barat Baviera, Claudia Bolognesi, Pier Sandro Cocconcelli, Riccardo Crebelli, David Michael Gott, Konrad Grob, Evgenia Lampi, Marcel Mengelers, Alicja Mortensen, Gilles Rivière, Inger‐Lise Steffensen, Christina Tlustos, Henk Van Loveren, Laurence Vernis, Holger Zorn, Yrjö Roos, Magdalena Andryszkiewicz, Yi Liu, Andrew Chesson
Format: Article
Language:English
Published: Wiley 2022-12-01
Series:EFSA Journal
Subjects:
Online Access:https://doi.org/10.2903/j.efsa.2022.7678
_version_ 1828085246993629184
author EFSA Panel on Food Contact Materials; Enzymes and Processing Aids (CEP)
Claude Lambré
José Manuel Barat Baviera
Claudia Bolognesi
Pier Sandro Cocconcelli
Riccardo Crebelli
David Michael Gott
Konrad Grob
Evgenia Lampi
Marcel Mengelers
Alicja Mortensen
Gilles Rivière
Inger‐Lise Steffensen
Christina Tlustos
Henk Van Loveren
Laurence Vernis
Holger Zorn
Yrjö Roos
Magdalena Andryszkiewicz
Yi Liu
Andrew Chesson
author_facet EFSA Panel on Food Contact Materials; Enzymes and Processing Aids (CEP)
Claude Lambré
José Manuel Barat Baviera
Claudia Bolognesi
Pier Sandro Cocconcelli
Riccardo Crebelli
David Michael Gott
Konrad Grob
Evgenia Lampi
Marcel Mengelers
Alicja Mortensen
Gilles Rivière
Inger‐Lise Steffensen
Christina Tlustos
Henk Van Loveren
Laurence Vernis
Holger Zorn
Yrjö Roos
Magdalena Andryszkiewicz
Yi Liu
Andrew Chesson
author_sort EFSA Panel on Food Contact Materials; Enzymes and Processing Aids (CEP)
collection DOAJ
description Abstract The food enzyme phytepsin (EC 3.4.23.40) is extracted from the pistils of cardoon (Cynara cardunculus L.) by QUALIFICA/oriGIn PORTUGAL. It is intended to be used in milk processing for cheese production. As no concerns arose from the source of the food enzyme, from its manufacture, and based on the history of safe use and consumption, the Panel considered that toxicological data and the estimation of dietary exposure were not required. The Panel considered that allergic reactions to this phytepsin cannot be excluded in individuals allergic to this plant. However, the likelihood of allergic reactions to the phytepsin from C. cardunculus L. is expected not to exceed the likelihood of allergic reactions to cardoon. As the prevalence of allergic reactions to cardoon is low, also the likelihood of such reaction to occur to the food enzyme is low. Based on the data provided, the Panel concluded that this food enzyme does not give rise to safety concerns under the intended conditions of use.
first_indexed 2024-04-11T04:36:13Z
format Article
id doaj.art-cbbaa819a7f74503bbcd68d1c08f0ef0
institution Directory Open Access Journal
issn 1831-4732
language English
last_indexed 2024-04-11T04:36:13Z
publishDate 2022-12-01
publisher Wiley
record_format Article
series EFSA Journal
spelling doaj.art-cbbaa819a7f74503bbcd68d1c08f0ef02022-12-28T12:23:02ZengWileyEFSA Journal1831-47322022-12-012012n/an/a10.2903/j.efsa.2022.7678Safety evaluation of the food enzyme phytepsin from Cynara cardunculus L.EFSA Panel on Food Contact Materials; Enzymes and Processing Aids (CEP)Claude LambréJosé Manuel Barat BavieraClaudia BolognesiPier Sandro CocconcelliRiccardo CrebelliDavid Michael GottKonrad GrobEvgenia LampiMarcel MengelersAlicja MortensenGilles RivièreInger‐Lise SteffensenChristina TlustosHenk Van LoverenLaurence VernisHolger ZornYrjö RoosMagdalena AndryszkiewiczYi LiuAndrew ChessonAbstract The food enzyme phytepsin (EC 3.4.23.40) is extracted from the pistils of cardoon (Cynara cardunculus L.) by QUALIFICA/oriGIn PORTUGAL. It is intended to be used in milk processing for cheese production. As no concerns arose from the source of the food enzyme, from its manufacture, and based on the history of safe use and consumption, the Panel considered that toxicological data and the estimation of dietary exposure were not required. The Panel considered that allergic reactions to this phytepsin cannot be excluded in individuals allergic to this plant. However, the likelihood of allergic reactions to the phytepsin from C. cardunculus L. is expected not to exceed the likelihood of allergic reactions to cardoon. As the prevalence of allergic reactions to cardoon is low, also the likelihood of such reaction to occur to the food enzyme is low. Based on the data provided, the Panel concluded that this food enzyme does not give rise to safety concerns under the intended conditions of use.https://doi.org/10.2903/j.efsa.2022.7678food enzymeplant coagulantphytepsincardosincyprosinEC 3.3.23.40
spellingShingle EFSA Panel on Food Contact Materials; Enzymes and Processing Aids (CEP)
Claude Lambré
José Manuel Barat Baviera
Claudia Bolognesi
Pier Sandro Cocconcelli
Riccardo Crebelli
David Michael Gott
Konrad Grob
Evgenia Lampi
Marcel Mengelers
Alicja Mortensen
Gilles Rivière
Inger‐Lise Steffensen
Christina Tlustos
Henk Van Loveren
Laurence Vernis
Holger Zorn
Yrjö Roos
Magdalena Andryszkiewicz
Yi Liu
Andrew Chesson
Safety evaluation of the food enzyme phytepsin from Cynara cardunculus L.
EFSA Journal
food enzyme
plant coagulant
phytepsin
cardosin
cyprosin
EC 3.3.23.40
title Safety evaluation of the food enzyme phytepsin from Cynara cardunculus L.
title_full Safety evaluation of the food enzyme phytepsin from Cynara cardunculus L.
title_fullStr Safety evaluation of the food enzyme phytepsin from Cynara cardunculus L.
title_full_unstemmed Safety evaluation of the food enzyme phytepsin from Cynara cardunculus L.
title_short Safety evaluation of the food enzyme phytepsin from Cynara cardunculus L.
title_sort safety evaluation of the food enzyme phytepsin from cynara cardunculus l
topic food enzyme
plant coagulant
phytepsin
cardosin
cyprosin
EC 3.3.23.40
url https://doi.org/10.2903/j.efsa.2022.7678
work_keys_str_mv AT efsapanelonfoodcontactmaterialsenzymesandprocessingaidscep safetyevaluationofthefoodenzymephytepsinfromcynaracardunculusl
AT claudelambre safetyevaluationofthefoodenzymephytepsinfromcynaracardunculusl
AT josemanuelbaratbaviera safetyevaluationofthefoodenzymephytepsinfromcynaracardunculusl
AT claudiabolognesi safetyevaluationofthefoodenzymephytepsinfromcynaracardunculusl
AT piersandrococconcelli safetyevaluationofthefoodenzymephytepsinfromcynaracardunculusl
AT riccardocrebelli safetyevaluationofthefoodenzymephytepsinfromcynaracardunculusl
AT davidmichaelgott safetyevaluationofthefoodenzymephytepsinfromcynaracardunculusl
AT konradgrob safetyevaluationofthefoodenzymephytepsinfromcynaracardunculusl
AT evgenialampi safetyevaluationofthefoodenzymephytepsinfromcynaracardunculusl
AT marcelmengelers safetyevaluationofthefoodenzymephytepsinfromcynaracardunculusl
AT alicjamortensen safetyevaluationofthefoodenzymephytepsinfromcynaracardunculusl
AT gillesriviere safetyevaluationofthefoodenzymephytepsinfromcynaracardunculusl
AT ingerlisesteffensen safetyevaluationofthefoodenzymephytepsinfromcynaracardunculusl
AT christinatlustos safetyevaluationofthefoodenzymephytepsinfromcynaracardunculusl
AT henkvanloveren safetyevaluationofthefoodenzymephytepsinfromcynaracardunculusl
AT laurencevernis safetyevaluationofthefoodenzymephytepsinfromcynaracardunculusl
AT holgerzorn safetyevaluationofthefoodenzymephytepsinfromcynaracardunculusl
AT yrjoroos safetyevaluationofthefoodenzymephytepsinfromcynaracardunculusl
AT magdalenaandryszkiewicz safetyevaluationofthefoodenzymephytepsinfromcynaracardunculusl
AT yiliu safetyevaluationofthefoodenzymephytepsinfromcynaracardunculusl
AT andrewchesson safetyevaluationofthefoodenzymephytepsinfromcynaracardunculusl