Effects of Lonomia obliqua Venom on Vascular Smooth Muscle Cells: Contribution of NADPH Oxidase-Derived Reactive Oxygen Species

Effects of Lonomia obliqua Venom on Vascular Smooth Muscle Cells: Contribution of NADPH Oxidase-Derived Reactive Oxygen Species

Envenomation caused by human contact with the caterpillar Lonomia is characterized by deleterious effects on coagulation and patency of blood vessels. The cellular effects induced by Lonomia obliqua venom highlights its capacity to activate endothelial cells, leading to a proinflammatory phenotype....

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Bibliographic Details
Main Authors: João Alfredo Moraes, Genilson Rodrigues, Vany Nascimento-Silva, Mariana Renovato-Martins, Markus Berger, Jorge Almeida Guimarães, Christina Barja-Fidalgo
Format: Article
Language:English
Published: MDPI AG 2017-11-01
Series:Toxins
Subjects:
Lonomia obliqua venom
vascular smooth muscle cells
reactive oxygen species
Online Access:https://www.mdpi.com/2072-6651/9/11/360

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