A very rare case of neuroendocrine carcinoma of stomach
We report an extremely rare case of neuroendocrine carcinoma (NEC) of the stomach, which is known for its aggressive behavior and poor prognosis. To the best of our knowledge, only a few cases have been reported in the world till date and our case may be one of the very few of this rare pathology. A...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2016-01-01
|
| Series: | CHRISMED Journal of Health and Research |
| Subjects: | |
| Online Access: | http://www.cjhr.org/article.asp?issn=2348-3334;year=2016;volume=3;issue=3;spage=236;epage=239;aulast=Purkayastha |
| _version_ | 1819149944895832064 |
|---|---|
| author | Abhishek Purkayastha Neelam Sharma Virender Suhag Vibha Dutta |
| author_facet | Abhishek Purkayastha Neelam Sharma Virender Suhag Vibha Dutta |
| author_sort | Abhishek Purkayastha |
| collection | DOAJ |
| description | We report an extremely rare case of neuroendocrine carcinoma (NEC) of the stomach, which is known for its aggressive behavior and poor prognosis. To the best of our knowledge, only a few cases have been reported in the world till date and our case may be one of the very few of this rare pathology. A 42-year-old male presented with vague abdominal pain and significant weight loss. Upper gastrointestinal endoscopy revealed ulceroproliferative growth in the pylorus. Computed tomography of the abdomen showed thickening of the pylorus with locoregional lymphadenopathy. Positron emission tomography scan showed localized disease. A distal gastrectomy with D1 dissection was performed. Postoperative histopathology revealed high grade NEC of the stomach with cytokeratin-20, epithelial membrane antigen, chromogranin, and CDX-2 positivity on immunohistochemistry. He was treated with adjuvant chemotherapy followed by locoregional radiotherapy with significant response to treatment. Presently on regular follow-up without any evidence of recurrence or distant metastasis. |
| first_indexed | 2024-12-22T14:09:40Z |
| format | Article |
| id | doaj.art-cbbb1a703db144829a9cf1c3135ed34d |
| institution | Directory Open Access Journal |
| issn | 2348-3334 2348-506X |
| language | English |
| last_indexed | 2024-12-22T14:09:40Z |
| publishDate | 2016-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | CHRISMED Journal of Health and Research |
| spelling | doaj.art-cbbb1a703db144829a9cf1c3135ed34d2022-12-21T18:23:13ZengWolters Kluwer Medknow PublicationsCHRISMED Journal of Health and Research2348-33342348-506X2016-01-013323623910.4103/2348-3334.183759A very rare case of neuroendocrine carcinoma of stomachAbhishek PurkayasthaNeelam SharmaVirender SuhagVibha DuttaWe report an extremely rare case of neuroendocrine carcinoma (NEC) of the stomach, which is known for its aggressive behavior and poor prognosis. To the best of our knowledge, only a few cases have been reported in the world till date and our case may be one of the very few of this rare pathology. A 42-year-old male presented with vague abdominal pain and significant weight loss. Upper gastrointestinal endoscopy revealed ulceroproliferative growth in the pylorus. Computed tomography of the abdomen showed thickening of the pylorus with locoregional lymphadenopathy. Positron emission tomography scan showed localized disease. A distal gastrectomy with D1 dissection was performed. Postoperative histopathology revealed high grade NEC of the stomach with cytokeratin-20, epithelial membrane antigen, chromogranin, and CDX-2 positivity on immunohistochemistry. He was treated with adjuvant chemotherapy followed by locoregional radiotherapy with significant response to treatment. Presently on regular follow-up without any evidence of recurrence or distant metastasis.http://www.cjhr.org/article.asp?issn=2348-3334;year=2016;volume=3;issue=3;spage=236;epage=239;aulast=PurkayasthaGastric neuroendocrine neoplasmsneuroendocrine carcinomaradiotherapystomach |
| spellingShingle | Abhishek Purkayastha Neelam Sharma Virender Suhag Vibha Dutta A very rare case of neuroendocrine carcinoma of stomach CHRISMED Journal of Health and Research Gastric neuroendocrine neoplasms neuroendocrine carcinoma radiotherapy stomach |
| title | A very rare case of neuroendocrine carcinoma of stomach |
| title_full | A very rare case of neuroendocrine carcinoma of stomach |
| title_fullStr | A very rare case of neuroendocrine carcinoma of stomach |
| title_full_unstemmed | A very rare case of neuroendocrine carcinoma of stomach |
| title_short | A very rare case of neuroendocrine carcinoma of stomach |
| title_sort | very rare case of neuroendocrine carcinoma of stomach |
| topic | Gastric neuroendocrine neoplasms neuroendocrine carcinoma radiotherapy stomach |
| url | http://www.cjhr.org/article.asp?issn=2348-3334;year=2016;volume=3;issue=3;spage=236;epage=239;aulast=Purkayastha |
| work_keys_str_mv | AT abhishekpurkayastha averyrarecaseofneuroendocrinecarcinomaofstomach AT neelamsharma averyrarecaseofneuroendocrinecarcinomaofstomach AT virendersuhag averyrarecaseofneuroendocrinecarcinomaofstomach AT vibhadutta averyrarecaseofneuroendocrinecarcinomaofstomach AT abhishekpurkayastha veryrarecaseofneuroendocrinecarcinomaofstomach AT neelamsharma veryrarecaseofneuroendocrinecarcinomaofstomach AT virendersuhag veryrarecaseofneuroendocrinecarcinomaofstomach AT vibhadutta veryrarecaseofneuroendocrinecarcinomaofstomach |