Cutaneous and Pulmonary Tuberculosis—Diagnostic and Therapeutic Difficulties in a Patient with Autoimmunity
Cutaneous tuberculosis (CTB) is a very rare disease and accounts for only 1–2% of cases of extrapulmonary tuberculosis (EPTB). Due to the variety of its clinical manifestations, the uncharacteristic appearance of its lesions, resembling other dermatoses in the early stages, and the limited experienc...
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| Format: | Article |
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MDPI AG
2023-02-01
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| Series: | Pathogens |
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| Online Access: | https://www.mdpi.com/2076-0817/12/2/331 |
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| author | Monika Kozińska Ewa Augustynowicz-Kopeć Andrzej Gamian Anna Chudzik Mariola Paściak Przemysław Zdziarski |
| author_facet | Monika Kozińska Ewa Augustynowicz-Kopeć Andrzej Gamian Anna Chudzik Mariola Paściak Przemysław Zdziarski |
| author_sort | Monika Kozińska |
| collection | DOAJ |
| description | Cutaneous tuberculosis (CTB) is a very rare disease and accounts for only 1–2% of cases of extrapulmonary tuberculosis (EPTB). Due to the variety of its clinical manifestations, the uncharacteristic appearance of its lesions, resembling other dermatoses in the early stages, and the limited experience of clinicians due to the rarity of CTB, diagnosis is very difficult. Particularly noteworthy is the fact that most cases of EPTB, including skin tuberculosis (TB), can be a manifestation of systemic involvement. In this paper, we present a case of an immunocompromised patient who was diagnosed with CTB almost a year after the first dermatological lesions were located on the lower extremities. At the same time, due to respiratory symptoms, a diagnosis of pulmonary TB (PTB) was made, and radiological and microbiological confirmations were obtained. |
| first_indexed | 2024-03-11T08:18:20Z |
| format | Article |
| id | doaj.art-cbc3ad86903748c58e2bc78e697c796d |
| institution | Directory Open Access Journal |
| issn | 2076-0817 |
| language | English |
| last_indexed | 2024-03-11T08:18:20Z |
| publishDate | 2023-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pathogens |
| spelling | doaj.art-cbc3ad86903748c58e2bc78e697c796d2023-11-16T22:35:10ZengMDPI AGPathogens2076-08172023-02-0112233110.3390/pathogens12020331Cutaneous and Pulmonary Tuberculosis—Diagnostic and Therapeutic Difficulties in a Patient with AutoimmunityMonika Kozińska0Ewa Augustynowicz-Kopeć1Andrzej Gamian2Anna Chudzik3Mariola Paściak4Przemysław Zdziarski5Department of Microbiology, National Tuberculosis and Lung Diseases Research Institute, Plocka 26, 01-138 Warsaw, PolandDepartment of Microbiology, National Tuberculosis and Lung Diseases Research Institute, Plocka 26, 01-138 Warsaw, PolandDepartment of Immunology of Infectious Diseases, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Rudolfa Weigla 12, 53-114 Wroclaw, PolandDepartment of Immunology of Infectious Diseases, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Rudolfa Weigla 12, 53-114 Wroclaw, PolandDepartment of Immunology of Infectious Diseases, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Rudolfa Weigla 12, 53-114 Wroclaw, PolandDepartment of Clinical Immunology and Pulmonary Disease, Lower Silesian Oncology, Pulmonology and Hematology Centre, P.O. Box 1818, 50-385 Wroclaw, PolandCutaneous tuberculosis (CTB) is a very rare disease and accounts for only 1–2% of cases of extrapulmonary tuberculosis (EPTB). Due to the variety of its clinical manifestations, the uncharacteristic appearance of its lesions, resembling other dermatoses in the early stages, and the limited experience of clinicians due to the rarity of CTB, diagnosis is very difficult. Particularly noteworthy is the fact that most cases of EPTB, including skin tuberculosis (TB), can be a manifestation of systemic involvement. In this paper, we present a case of an immunocompromised patient who was diagnosed with CTB almost a year after the first dermatological lesions were located on the lower extremities. At the same time, due to respiratory symptoms, a diagnosis of pulmonary TB (PTB) was made, and radiological and microbiological confirmations were obtained.https://www.mdpi.com/2076-0817/12/2/331cutaneous tuberculosisextrapulmonary TBpulmonary TB<i>Mycobacterium tuberculosis</i> complexskin infections |
| spellingShingle | Monika Kozińska Ewa Augustynowicz-Kopeć Andrzej Gamian Anna Chudzik Mariola Paściak Przemysław Zdziarski Cutaneous and Pulmonary Tuberculosis—Diagnostic and Therapeutic Difficulties in a Patient with Autoimmunity Pathogens cutaneous tuberculosis extrapulmonary TB pulmonary TB <i>Mycobacterium tuberculosis</i> complex skin infections |
| title | Cutaneous and Pulmonary Tuberculosis—Diagnostic and Therapeutic Difficulties in a Patient with Autoimmunity |
| title_full | Cutaneous and Pulmonary Tuberculosis—Diagnostic and Therapeutic Difficulties in a Patient with Autoimmunity |
| title_fullStr | Cutaneous and Pulmonary Tuberculosis—Diagnostic and Therapeutic Difficulties in a Patient with Autoimmunity |
| title_full_unstemmed | Cutaneous and Pulmonary Tuberculosis—Diagnostic and Therapeutic Difficulties in a Patient with Autoimmunity |
| title_short | Cutaneous and Pulmonary Tuberculosis—Diagnostic and Therapeutic Difficulties in a Patient with Autoimmunity |
| title_sort | cutaneous and pulmonary tuberculosis diagnostic and therapeutic difficulties in a patient with autoimmunity |
| topic | cutaneous tuberculosis extrapulmonary TB pulmonary TB <i>Mycobacterium tuberculosis</i> complex skin infections |
| url | https://www.mdpi.com/2076-0817/12/2/331 |
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