Factors associated with hospital emergency readmission and mortality rates in patients with heart failure or chronic obstructive pulmonary disease: a national observational study

Background: Heart failure (HF) and chronic obstructive pulmonary disease (COPD) lead to unplanned hospital activity, but our understanding of what drives this is incomplete. Objectives: To model patient, primary care and hospital factors associated with readmission and mortality for patients with HF...

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Main Authors: Alex Bottle, Kate Honeyford, Faiza Chowdhury, Derek Bell, Paul Aylin
Format: Article
Language:English
Published: National Institute for Health Research 2018-07-01
Series:Health Services and Delivery Research
Subjects:
Online Access:https://doi.org/10.3310/hsdr06260
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author Alex Bottle
Kate Honeyford
Faiza Chowdhury
Derek Bell
Paul Aylin
author_facet Alex Bottle
Kate Honeyford
Faiza Chowdhury
Derek Bell
Paul Aylin
author_sort Alex Bottle
collection DOAJ
description Background: Heart failure (HF) and chronic obstructive pulmonary disease (COPD) lead to unplanned hospital activity, but our understanding of what drives this is incomplete. Objectives: To model patient, primary care and hospital factors associated with readmission and mortality for patients with HF and COPD, to assess the statistical performance of post-discharge emergency department (ED) attendance compared with readmission metrics and to compare all the results for the two conditions. Design: Observational study. Setting: English NHS. Participants: All patients admitted to acute non-specialist hospitals as an emergency for HF or COPD. Interventions: None. Main outcome measures: One-year mortality and 30-day emergency readmission following the patient’s first unplanned admission (‘index admission’) for HF or COPD. Data sources: Patient-level data from Hospital Episodes Statistics were combined with publicly available practice- and hospital-level data on performance, patient and staff experience and rehabilitation programme website information. Results: One-year mortality rates were 39.6% for HF and 24.1% for COPD and 30-day readmission rates were 19.8% for HF and 16.5% for COPD. Most patients were elderly with multiple comorbidities. Patient factors predicting mortality included older age, male sex, white ethnicity, prior missed outpatient appointments, (long) index length of hospital stay (LOS) and several comorbidities. Older age, missed appointments, (short) LOS and comorbidities also predicted readmission. Of the practice and hospital factors we considered, only more doctors per 10 beds [odds ratio (OR) 0.95 per doctor; p < 0.001] was significant for both cohorts for mortality, with staff recommending to friends and family (OR 0.80 per unit increase; p < 0.001) and number of general practitioners (GPs) per 1000 patients (OR 0.89 per extra GP; p = 0.004) important for COPD. For readmission, only hospital size [OR per 100 beds = 2.16, 95% confidence interval (CI) 1.34 to 3.48 for HF, and 2.27, 95% CI 1.40 to 3.66 for COPD] and doctors per 10 beds (OR 0.98; p < 0.001) were significantly associated. Some factors, such as comorbidities, varied in importance depending on the readmission diagnosis. ED visits were common after the index discharge, with 75% resulting in admission. Many predictors of admission at this visit were as for readmission minus comorbidities and plus attendance outside the day shift and numbers of admissions that hour. Hospital-level rates for ED attendance varied much more than those for readmission, but the omega statistics favoured them as a performance indicator. Limitations: Data lacked direct information on disease severity and ED attendance reasons; NHS surveys were not specific to HF or COPD patients; and some data sets were aggregated. Conclusions: Following an index admission for HF or COPD, older age, prior missed outpatient appointments, LOS and many comorbidities predict both mortality and readmission. Of the aggregated practice and hospital information, only doctors per bed and numbers of hospital beds were strongly associated with either outcome (both negatively). The 30-day ED visits and diagnosis-specific readmission rates seem to be useful performance indicators. Future work: Hospital variations in ED visits could be investigated using existing data despite coding limitations. Primary care management could be explored using individual-level linked databases. Funding: The National Institute for Health Research Health Services and Delivery Research programme.
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spelling doaj.art-cbd0cf4462fb45cabd7997e67dad83032022-12-22T01:16:18ZengNational Institute for Health ResearchHealth Services and Delivery Research2050-43492050-43572018-07-0162610.3310/hsdr0626014/19/50Factors associated with hospital emergency readmission and mortality rates in patients with heart failure or chronic obstructive pulmonary disease: a national observational studyAlex Bottle0Kate Honeyford1Faiza Chowdhury2Derek Bell3Paul Aylin4Dr Foster Unit, Department of Primary Care and Public Health, Imperial College London, London, UKDr Foster Unit, Department of Primary Care and Public Health, Imperial College London, London, UKDepartment of Acute Medicine, Chelsea and Westminster Hospital, Imperial College London, London, UKDepartment of Acute Medicine, Chelsea and Westminster Hospital, Imperial College London, London, UKDr Foster Unit, Department of Primary Care and Public Health, Imperial College London, London, UKBackground: Heart failure (HF) and chronic obstructive pulmonary disease (COPD) lead to unplanned hospital activity, but our understanding of what drives this is incomplete. Objectives: To model patient, primary care and hospital factors associated with readmission and mortality for patients with HF and COPD, to assess the statistical performance of post-discharge emergency department (ED) attendance compared with readmission metrics and to compare all the results for the two conditions. Design: Observational study. Setting: English NHS. Participants: All patients admitted to acute non-specialist hospitals as an emergency for HF or COPD. Interventions: None. Main outcome measures: One-year mortality and 30-day emergency readmission following the patient’s first unplanned admission (‘index admission’) for HF or COPD. Data sources: Patient-level data from Hospital Episodes Statistics were combined with publicly available practice- and hospital-level data on performance, patient and staff experience and rehabilitation programme website information. Results: One-year mortality rates were 39.6% for HF and 24.1% for COPD and 30-day readmission rates were 19.8% for HF and 16.5% for COPD. Most patients were elderly with multiple comorbidities. Patient factors predicting mortality included older age, male sex, white ethnicity, prior missed outpatient appointments, (long) index length of hospital stay (LOS) and several comorbidities. Older age, missed appointments, (short) LOS and comorbidities also predicted readmission. Of the practice and hospital factors we considered, only more doctors per 10 beds [odds ratio (OR) 0.95 per doctor; p < 0.001] was significant for both cohorts for mortality, with staff recommending to friends and family (OR 0.80 per unit increase; p < 0.001) and number of general practitioners (GPs) per 1000 patients (OR 0.89 per extra GP; p = 0.004) important for COPD. For readmission, only hospital size [OR per 100 beds = 2.16, 95% confidence interval (CI) 1.34 to 3.48 for HF, and 2.27, 95% CI 1.40 to 3.66 for COPD] and doctors per 10 beds (OR 0.98; p < 0.001) were significantly associated. Some factors, such as comorbidities, varied in importance depending on the readmission diagnosis. ED visits were common after the index discharge, with 75% resulting in admission. Many predictors of admission at this visit were as for readmission minus comorbidities and plus attendance outside the day shift and numbers of admissions that hour. Hospital-level rates for ED attendance varied much more than those for readmission, but the omega statistics favoured them as a performance indicator. Limitations: Data lacked direct information on disease severity and ED attendance reasons; NHS surveys were not specific to HF or COPD patients; and some data sets were aggregated. Conclusions: Following an index admission for HF or COPD, older age, prior missed outpatient appointments, LOS and many comorbidities predict both mortality and readmission. Of the aggregated practice and hospital information, only doctors per bed and numbers of hospital beds were strongly associated with either outcome (both negatively). The 30-day ED visits and diagnosis-specific readmission rates seem to be useful performance indicators. Future work: Hospital variations in ED visits could be investigated using existing data despite coding limitations. Primary care management could be explored using individual-level linked databases. Funding: The National Institute for Health Research Health Services and Delivery Research programme.https://doi.org/10.3310/hsdr06260heart failurecomorbiditylength of stayoutcome assessment (health care)patient readmissionpulmonary diseasechronic obstructive
spellingShingle Alex Bottle
Kate Honeyford
Faiza Chowdhury
Derek Bell
Paul Aylin
Factors associated with hospital emergency readmission and mortality rates in patients with heart failure or chronic obstructive pulmonary disease: a national observational study
Health Services and Delivery Research
heart failure
comorbidity
length of stay
outcome assessment (health care)
patient readmission
pulmonary disease
chronic obstructive
title Factors associated with hospital emergency readmission and mortality rates in patients with heart failure or chronic obstructive pulmonary disease: a national observational study
title_full Factors associated with hospital emergency readmission and mortality rates in patients with heart failure or chronic obstructive pulmonary disease: a national observational study
title_fullStr Factors associated with hospital emergency readmission and mortality rates in patients with heart failure or chronic obstructive pulmonary disease: a national observational study
title_full_unstemmed Factors associated with hospital emergency readmission and mortality rates in patients with heart failure or chronic obstructive pulmonary disease: a national observational study
title_short Factors associated with hospital emergency readmission and mortality rates in patients with heart failure or chronic obstructive pulmonary disease: a national observational study
title_sort factors associated with hospital emergency readmission and mortality rates in patients with heart failure or chronic obstructive pulmonary disease a national observational study
topic heart failure
comorbidity
length of stay
outcome assessment (health care)
patient readmission
pulmonary disease
chronic obstructive
url https://doi.org/10.3310/hsdr06260
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