Human Vitamin K Epoxide Reductase as a Target of Its Redox Protein

Human Vitamin K Epoxide Reductase as a Target of Its Redox Protein

Human vitamin K epoxide reductase (hVKORC1) enzymatic activity requires an initial activation by a specific redox protein, a less studied step in the hVKORC1 vital cycle. Significant steric conditions must be met by enzymes, being that to adapt their configurations is mandatory for hVKORC1 activatio...

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Bibliographic Details
Main Authors: Julie Ledoux, Maxim Stolyarchuk, Enki Bachelier, Alain Trouvé, Luba Tchertanov
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:International Journal of Molecular Sciences
Subjects:
human vitamin K epoxide reductase
hVKORC1
blood coagulation
redox protein target
enzyme activation
modular protein
Online Access:https://www.mdpi.com/1422-0067/23/7/3899

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