APOBEC-1 deletion enhances cisplatin-induced acute kidney injury

APOBEC-1 deletion enhances cisplatin-induced acute kidney injury

Abstract Cisplatin (CP) induces acute kidney injury (AKI) whereby proximal tubules undergo regulated necrosis. Repair is almost complete after a single dose. We now demonstrate a role for Apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 (Apobec-1) that is prominently expressed at the in...

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Bibliographic Details
Main Authors:	Xiaojia Guo, Valerie Blanc, Nicholas O. Davidson, Heino Velazquez, Tian-min Chen, Dennis G. Moledina, Gilbert W. Moeckel, Robert L. Safirstein, Gary V. Desir
Format:	Article
Language:	English
Published:	Nature Portfolio 2023-12-01
Series:	Scientific Reports
Online Access:	https://doi.org/10.1038/s41598-023-49575-3

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