Clinical and histological criteria for sex cord ovarian stromal tumors

Aim: to identify clinical and histological criteria for sex cord ovarian stromal tumors (OSTs).Materials and Methods. The retrospective non-comparative study was based on the main inclusion such as histologically verified sex cord OSTs. A standard examination algorithm was analyzed (ultrasound, bloo...

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Main Authors: A. М. Beishembaev, K. I. Zhordania
Format: Article
Language:Russian
Published: IRBIS LLC 2020-09-01
Series:Акушерство, гинекология и репродукция
Subjects:
Online Access:https://www.gynecology.su/jour/article/view/777
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author A. М. Beishembaev
K. I. Zhordania
author_facet A. М. Beishembaev
K. I. Zhordania
author_sort A. М. Beishembaev
collection DOAJ
description Aim: to identify clinical and histological criteria for sex cord ovarian stromal tumors (OSTs).Materials and Methods. The retrospective non-comparative study was based on the main inclusion such as histologically verified sex cord OSTs. A standard examination algorithm was analyzed (ultrasound, blood tests, CT or MRI of the abdominal and pelvic organs). All clinical data were obtained from patients treated and monitored in clinical units at the Blokhin National Medical Research Center of Oncology and the National Center of Oncology and Hematology of the Kyrgyz Republic.Results. Data were obtained on the frequency of necrobiotic changes, malignancy, disease stages and their impact on survival in 456 patients. The 10-year survival rate for OSTs patients with vs. without intra-tumor necrobiotic changes was significantly lower (17.2 % and 78.1 %, respectively).Conclusion. The main factors of unfavorable prognosis in patients with granulosa cell ovarian tumors were disease stage and intra-tumor necrobiotic changes.
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spelling doaj.art-cbd8e8af1ca643fba882e4f680d1bbf52023-03-13T07:09:50ZrusIRBIS LLCАкушерство, гинекология и репродукция2313-73472500-31942020-09-0114326126810.17749/2313-7347/ob.gyn.rep.2020.126565Clinical and histological criteria for sex cord ovarian stromal tumorsA. М. Beishembaev0K. I. Zhordania1Kyrgyz State Medical Institute of Advanced Training and Retraining named after S. B. Daniyarov, Health Ministry of Kyrgyz RepublicN.N. Blokhin National Medical Research Center of Oncology, Health Ministry of Russian FederationAim: to identify clinical and histological criteria for sex cord ovarian stromal tumors (OSTs).Materials and Methods. The retrospective non-comparative study was based on the main inclusion such as histologically verified sex cord OSTs. A standard examination algorithm was analyzed (ultrasound, blood tests, CT or MRI of the abdominal and pelvic organs). All clinical data were obtained from patients treated and monitored in clinical units at the Blokhin National Medical Research Center of Oncology and the National Center of Oncology and Hematology of the Kyrgyz Republic.Results. Data were obtained on the frequency of necrobiotic changes, malignancy, disease stages and their impact on survival in 456 patients. The 10-year survival rate for OSTs patients with vs. without intra-tumor necrobiotic changes was significantly lower (17.2 % and 78.1 %, respectively).Conclusion. The main factors of unfavorable prognosis in patients with granulosa cell ovarian tumors were disease stage and intra-tumor necrobiotic changes.https://www.gynecology.su/jour/article/view/777ovarian stromal tumorsgranulosa cell ovarian tumorsovarian ginandroblastomaovarian cancer
spellingShingle A. М. Beishembaev
K. I. Zhordania
Clinical and histological criteria for sex cord ovarian stromal tumors
Акушерство, гинекология и репродукция
ovarian stromal tumors
granulosa cell ovarian tumors
ovarian ginandroblastoma
ovarian cancer
title Clinical and histological criteria for sex cord ovarian stromal tumors
title_full Clinical and histological criteria for sex cord ovarian stromal tumors
title_fullStr Clinical and histological criteria for sex cord ovarian stromal tumors
title_full_unstemmed Clinical and histological criteria for sex cord ovarian stromal tumors
title_short Clinical and histological criteria for sex cord ovarian stromal tumors
title_sort clinical and histological criteria for sex cord ovarian stromal tumors
topic ovarian stromal tumors
granulosa cell ovarian tumors
ovarian ginandroblastoma
ovarian cancer
url https://www.gynecology.su/jour/article/view/777
work_keys_str_mv AT ambeishembaev clinicalandhistologicalcriteriaforsexcordovarianstromaltumors
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