Variation of polypharmacy in older primary care attenders occurs at prescriber level

Abstract Background Polypharmacy is particularly important in older persons as they are more likely to experience adverse events compared to the rest of the population. Despite the relevance, there is a lack of studies on the possible association of patient, prescriber and practice characteristics w...

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Main Authors: Su Miin Ong, Yvonne Mei Fong Lim, Sheamini Sivasampu, Ee Ming Khoo
Format: Article
Language:English
Published: BMC 2018-02-01
Series:BMC Geriatrics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12877-018-0750-2
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author Su Miin Ong
Yvonne Mei Fong Lim
Sheamini Sivasampu
Ee Ming Khoo
author_facet Su Miin Ong
Yvonne Mei Fong Lim
Sheamini Sivasampu
Ee Ming Khoo
author_sort Su Miin Ong
collection DOAJ
description Abstract Background Polypharmacy is particularly important in older persons as they are more likely to experience adverse events compared to the rest of the population. Despite the relevance, there is a lack of studies on the possible association of patient, prescriber and practice characteristics with polypharmacy. Thus, the aim of this study was to determine the rate of polypharmacy among older persons attending public and private primary care clinics, and its association with patient, prescriber and practice characteristics. Methods We used data from The National Medical Care Survey (NMCS), a national cross-sectional survey of patients’ visits to primary care clinics in Malaysia. A weighted total of 22,832 encounters of patients aged ≥65 years were analysed. Polypharmacy was defined as concomitant use of five medications and above. Multilevel logistic regression was performed to examine the association of polypharmacy with patient, prescriber and practice characteristics. Results A total of 20.3% of the older primary care attenders experienced polypharmacy (26.7%% in public and 11.0% in private practice). The adjusted odds ratio (OR) of polypharmacy were 6.37 times greater in public practices. Polypharmacy was associated with patients of female gender (OR 1.49), primary education level (OR 1.61) and multimorbidity (OR 14.21). The variation in rate of polypharmacy was mainly found at prescriber level. Conclusion Polypharmacy is common among older persons visiting primary care practices. Given the possible adverse outcomes, interventions to reduce the burden of polypharmacy are best to be directed at individual prescribers.
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spelling doaj.art-cbd97da137c44953a10bafe639db661b2022-12-22T00:45:47ZengBMCBMC Geriatrics1471-23182018-02-0118111210.1186/s12877-018-0750-2Variation of polypharmacy in older primary care attenders occurs at prescriber levelSu Miin Ong0Yvonne Mei Fong Lim1Sheamini Sivasampu2Ee Ming Khoo3Healthcare Statistics Unit, National Clinical Research CentreHealthcare Statistics Unit, National Clinical Research CentreHealthcare Statistics Unit, National Clinical Research CentreDepartment of Primary Care Medicine, Faculty of Medicine, University of MalayaAbstract Background Polypharmacy is particularly important in older persons as they are more likely to experience adverse events compared to the rest of the population. Despite the relevance, there is a lack of studies on the possible association of patient, prescriber and practice characteristics with polypharmacy. Thus, the aim of this study was to determine the rate of polypharmacy among older persons attending public and private primary care clinics, and its association with patient, prescriber and practice characteristics. Methods We used data from The National Medical Care Survey (NMCS), a national cross-sectional survey of patients’ visits to primary care clinics in Malaysia. A weighted total of 22,832 encounters of patients aged ≥65 years were analysed. Polypharmacy was defined as concomitant use of five medications and above. Multilevel logistic regression was performed to examine the association of polypharmacy with patient, prescriber and practice characteristics. Results A total of 20.3% of the older primary care attenders experienced polypharmacy (26.7%% in public and 11.0% in private practice). The adjusted odds ratio (OR) of polypharmacy were 6.37 times greater in public practices. Polypharmacy was associated with patients of female gender (OR 1.49), primary education level (OR 1.61) and multimorbidity (OR 14.21). The variation in rate of polypharmacy was mainly found at prescriber level. Conclusion Polypharmacy is common among older persons visiting primary care practices. Given the possible adverse outcomes, interventions to reduce the burden of polypharmacy are best to be directed at individual prescribers.http://link.springer.com/article/10.1186/s12877-018-0750-2EpidemiologyMedicationMultimorbidityMultilevel modelling
spellingShingle Su Miin Ong
Yvonne Mei Fong Lim
Sheamini Sivasampu
Ee Ming Khoo
Variation of polypharmacy in older primary care attenders occurs at prescriber level
BMC Geriatrics
Epidemiology
Medication
Multimorbidity
Multilevel modelling
title Variation of polypharmacy in older primary care attenders occurs at prescriber level
title_full Variation of polypharmacy in older primary care attenders occurs at prescriber level
title_fullStr Variation of polypharmacy in older primary care attenders occurs at prescriber level
title_full_unstemmed Variation of polypharmacy in older primary care attenders occurs at prescriber level
title_short Variation of polypharmacy in older primary care attenders occurs at prescriber level
title_sort variation of polypharmacy in older primary care attenders occurs at prescriber level
topic Epidemiology
Medication
Multimorbidity
Multilevel modelling
url http://link.springer.com/article/10.1186/s12877-018-0750-2
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AT eemingkhoo variationofpolypharmacyinolderprimarycareattendersoccursatprescriberlevel