Research Advances in Enzymatic Detoxification of Deoxynivalenol

Deoxynivalenol (DON) is a toxic secondary metabolite produced by Fusarium spp. that mainly contaminates wheat, corn, and other food crops, and has posed serious threats to food safety. Currently, enzymatic detoxification of DON shows promising application prospects. This paper provided an overview o...

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Main Authors: SUN Jing, ZHAO Cheng-cheng, DU Wen, HAN Yang-ying, ZHAO Yi-fan, LIU Hu-jun
Format: Article
Language:English
Published: Academy of National Food and Strategic Reserves Administration 2024-03-01
Series:Liang you shipin ke-ji
Subjects:
Online Access:http://lyspkj.ijournal.cn/lyspkj/article/abstract/20240216
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author SUN Jing
ZHAO Cheng-cheng
DU Wen
HAN Yang-ying
ZHAO Yi-fan
LIU Hu-jun
author_facet SUN Jing
ZHAO Cheng-cheng
DU Wen
HAN Yang-ying
ZHAO Yi-fan
LIU Hu-jun
author_sort SUN Jing
collection DOAJ
description Deoxynivalenol (DON) is a toxic secondary metabolite produced by Fusarium spp. that mainly contaminates wheat, corn, and other food crops, and has posed serious threats to food safety. Currently, enzymatic detoxification of DON shows promising application prospects. This paper provided an overview of the latest domestic and international research on the types of biotransformation enzymes, degradation mechanisms, structural features, detoxification enzyme mining strategies, and molecular modifications of DON. Additionally, the paper explored research trends in molecular design of mycotoxin detoxification enzymes assisted by artificial intelligence, which aimed to provide a reference for the development of bio-detoxification technology of DON in food and feed.
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spelling doaj.art-cbdabc1ddb474398981c244cd7c9df862024-03-28T03:18:49ZengAcademy of National Food and Strategic Reserves AdministrationLiang you shipin ke-ji1007-75612024-03-0132212112610.16210/j.cnki.1007-7561.2024.02.015Research Advances in Enzymatic Detoxification of DeoxynivalenolSUN Jing0ZHAO Cheng-cheng1DU Wen2HAN Yang-ying3ZHAO Yi-fan4LIU Hu-jun5Institute of Cereal and Oil Science and Technology, Academy of National Food and Strategic Reserves Administration, Beijing 100037, ChinaInstitute of Cereal and Oil Science and Technology, Academy of National Food and Strategic Reserves Administration, Beijing 100037, ChinaInstitute of Cereal and Oil Science and Technology, Academy of National Food and Strategic Reserves Administration, Beijing 100037, ChinaInstitute of Cereal and Oil Science and Technology, Academy of National Food and Strategic Reserves Administration, Beijing 100037, ChinaInstitute of Cereal and Oil Science and Technology, Academy of National Food and Strategic Reserves Administration, Beijing 100037, ChinaInstitute of Cereal and Oil Science and Technology, Academy of National Food and Strategic Reserves Administration, Beijing 100037, ChinaDeoxynivalenol (DON) is a toxic secondary metabolite produced by Fusarium spp. that mainly contaminates wheat, corn, and other food crops, and has posed serious threats to food safety. Currently, enzymatic detoxification of DON shows promising application prospects. This paper provided an overview of the latest domestic and international research on the types of biotransformation enzymes, degradation mechanisms, structural features, detoxification enzyme mining strategies, and molecular modifications of DON. Additionally, the paper explored research trends in molecular design of mycotoxin detoxification enzymes assisted by artificial intelligence, which aimed to provide a reference for the development of bio-detoxification technology of DON in food and feed.http://lyspkj.ijournal.cn/lyspkj/article/abstract/20240216deoxynivalenolbiological enzymebio-degradationmolecular modificationfood safety
spellingShingle SUN Jing
ZHAO Cheng-cheng
DU Wen
HAN Yang-ying
ZHAO Yi-fan
LIU Hu-jun
Research Advances in Enzymatic Detoxification of Deoxynivalenol
Liang you shipin ke-ji
deoxynivalenol
biological enzyme
bio-degradation
molecular modification
food safety
title Research Advances in Enzymatic Detoxification of Deoxynivalenol
title_full Research Advances in Enzymatic Detoxification of Deoxynivalenol
title_fullStr Research Advances in Enzymatic Detoxification of Deoxynivalenol
title_full_unstemmed Research Advances in Enzymatic Detoxification of Deoxynivalenol
title_short Research Advances in Enzymatic Detoxification of Deoxynivalenol
title_sort research advances in enzymatic detoxification of deoxynivalenol
topic deoxynivalenol
biological enzyme
bio-degradation
molecular modification
food safety
url http://lyspkj.ijournal.cn/lyspkj/article/abstract/20240216
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