Factors of cardiovascular risk and intervisit arterial pressure variability
The aim: To determine the relationship between modified, unmodified cardiovascular risk factors (CRF) and intervisit arterial pressure variability (IAPW) in men of working age with arterial hypertension (AH). Material and methods. We examined 160 men with uncomplicated AH, among them, 82 patients ha...
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| Format: | Article |
| Language: | English |
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State Institution of Science «Research and Practical Center of Preventive and Clinical Medicine» State Administrative Department
2019-06-01
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| Series: | Клінічна та профілактична медицина |
| Subjects: | |
| Online Access: | https://cp-medical.com/index.php/journal/article/view/47 |
| _version_ | 1797658248252227584 |
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| author | T.I. Nimtsovych O.Y. Mischeniuk A.M. Kravchenko |
| author_facet | T.I. Nimtsovych O.Y. Mischeniuk A.M. Kravchenko |
| author_sort | T.I. Nimtsovych |
| collection | DOAJ |
| description | The aim: To determine the relationship between modified, unmodified cardiovascular risk factors (CRF) and intervisit arterial pressure variability (IAPW) in men of working age with arterial hypertension (AH).
Material and methods. We examined 160 men with uncomplicated AH, among them, 82 patients had high IAPW, and 78 patients – low IAPW. The average age in patients with high and low IAPW did not differ and was 50.65 ± 6.14 and 50.26 ± 6.27 years, respectively (p = 0.689). Indices of IAPW were calculated based on the standard deviation (SD) of measurements of office blood pressure during 4 visits to the clinic. The criterion for high IAPW was the value of systolic arterial pressor (AP) – 15 / 15 mm Hg (day / night), for diastolic AP – 14/12 mm Hg (day / night). The analysis was carried out using standard statistical methods for parametric and non-parametric parameters.
Results. It has been established, that the frequency of both modified and unmodified risk factors is greater in patients with hypertension and high IAPW, than in patients with low IAPW. The presence of obesity (36 of 82 versus 7 of 78; р ≤ 0.0001), family anamnesis (71 of 82 versus 52 of 78; p = 0.004), smoking episodes (62 of 82 versus 12 of 78; р ≤ 0.0001) and alcohol use (24 of 82 versus 2 of 78; p ≤ 0.0001) is significantly more common in patients with high IAPW, than in patients with low level of IAPW. There was a direct correlation between the MBA value and the percentage of 10-year risk of cardiovascular death on the SCORE scale (r = 0.47; p ≤ 0.0001) іn patients with hypertension.
Conclusion. The results of the study confirm the hypothesis that, it is expedient to determine IAPW in patients with AH, as an independent prognostic risk factor for cardiovascular complications. |
| first_indexed | 2024-03-11T17:57:26Z |
| format | Article |
| id | doaj.art-cbdb68d7ca7e461f8655b32c4531a711 |
| institution | Directory Open Access Journal |
| issn | 2616-4868 |
| language | English |
| last_indexed | 2024-03-11T17:57:26Z |
| publishDate | 2019-06-01 |
| publisher | State Institution of Science «Research and Practical Center of Preventive and Clinical Medicine» State Administrative Department |
| record_format | Article |
| series | Клінічна та профілактична медицина |
| spelling | doaj.art-cbdb68d7ca7e461f8655b32c4531a7112023-10-17T12:06:48ZengState Institution of Science «Research and Practical Center of Preventive and Clinical Medicine» State Administrative DepartmentКлінічна та профілактична медицина2616-48682019-06-011172410.31612/2616-4868.1(7).2019.0347Factors of cardiovascular risk and intervisit arterial pressure variabilityT.I. Nimtsovych0O.Y. Mischeniuk1A.M. Kravchenko2State Institution of Science “Research and Practical Center of Preventive and Clinical Medicine” State Administrative Department, Kyiv, Ukraine, Khmelnytskyi Regional Cardiologic Dispensary, Khmelnytskyi, UkraineState Institution of Science “Research and Practical Center of Preventive and Clinical Medicine” State Administrative Department, Kyiv, UkraineState Institution of Science “Research and Practical Center of Preventive and Clinical Medicine” State Administrative Department, Kyiv, UkraineThe aim: To determine the relationship between modified, unmodified cardiovascular risk factors (CRF) and intervisit arterial pressure variability (IAPW) in men of working age with arterial hypertension (AH). Material and methods. We examined 160 men with uncomplicated AH, among them, 82 patients had high IAPW, and 78 patients – low IAPW. The average age in patients with high and low IAPW did not differ and was 50.65 ± 6.14 and 50.26 ± 6.27 years, respectively (p = 0.689). Indices of IAPW were calculated based on the standard deviation (SD) of measurements of office blood pressure during 4 visits to the clinic. The criterion for high IAPW was the value of systolic arterial pressor (AP) – 15 / 15 mm Hg (day / night), for diastolic AP – 14/12 mm Hg (day / night). The analysis was carried out using standard statistical methods for parametric and non-parametric parameters. Results. It has been established, that the frequency of both modified and unmodified risk factors is greater in patients with hypertension and high IAPW, than in patients with low IAPW. The presence of obesity (36 of 82 versus 7 of 78; р ≤ 0.0001), family anamnesis (71 of 82 versus 52 of 78; p = 0.004), smoking episodes (62 of 82 versus 12 of 78; р ≤ 0.0001) and alcohol use (24 of 82 versus 2 of 78; p ≤ 0.0001) is significantly more common in patients with high IAPW, than in patients with low level of IAPW. There was a direct correlation between the MBA value and the percentage of 10-year risk of cardiovascular death on the SCORE scale (r = 0.47; p ≤ 0.0001) іn patients with hypertension. Conclusion. The results of the study confirm the hypothesis that, it is expedient to determine IAPW in patients with AH, as an independent prognostic risk factor for cardiovascular complications.https://cp-medical.com/index.php/journal/article/view/47risk factors, arterial hypertension, intervisit arterial pressure variability |
| spellingShingle | T.I. Nimtsovych O.Y. Mischeniuk A.M. Kravchenko Factors of cardiovascular risk and intervisit arterial pressure variability Клінічна та профілактична медицина risk factors, arterial hypertension, intervisit arterial pressure variability |
| title | Factors of cardiovascular risk and intervisit arterial pressure variability |
| title_full | Factors of cardiovascular risk and intervisit arterial pressure variability |
| title_fullStr | Factors of cardiovascular risk and intervisit arterial pressure variability |
| title_full_unstemmed | Factors of cardiovascular risk and intervisit arterial pressure variability |
| title_short | Factors of cardiovascular risk and intervisit arterial pressure variability |
| title_sort | factors of cardiovascular risk and intervisit arterial pressure variability |
| topic | risk factors, arterial hypertension, intervisit arterial pressure variability |
| url | https://cp-medical.com/index.php/journal/article/view/47 |
| work_keys_str_mv | AT tinimtsovych factorsofcardiovascularriskandintervisitarterialpressurevariability AT oymischeniuk factorsofcardiovascularriskandintervisitarterialpressurevariability AT amkravchenko factorsofcardiovascularriskandintervisitarterialpressurevariability |