Outcome of Early and Late Induction of Labour in Premature Rupture of Membranes

Objective: To determine the frequency of early and late labour induction in premature rupture of membranes and compare their outcome. Study Design: Cross sectional study. Place and Duration of Study: Department of Obstetrics & Gynaecology, Combined Military Hospital, Rawalpindi Pakistan,f...

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Main Authors: Amina Sohail, Mahum ., Tabassum Muzaffar, Uzma Saleem, Ali Mujtaba Tahir, Hafiz Zulqarnain
Format: Article
Language:English
Published: Army Medical College Rawalpindi 2023-01-01
Series:Pakistan Armed Forces Medical Journal
Subjects:
Online Access:https://pafmj.org/index.php/PAFMJ/article/view/8164
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author Amina Sohail
Mahum .
Tabassum Muzaffar
Uzma Saleem
Ali Mujtaba Tahir
Hafiz Zulqarnain
author_facet Amina Sohail
Mahum .
Tabassum Muzaffar
Uzma Saleem
Ali Mujtaba Tahir
Hafiz Zulqarnain
author_sort Amina Sohail
collection DOAJ
description Objective: To determine the frequency of early and late labour induction in premature rupture of membranes and compare their outcome. Study Design: Cross sectional study. Place and Duration of Study: Department of Obstetrics & Gynaecology, Combined Military Hospital, Rawalpindi Pakistan,from Jan-Dec 2021. Methodology: One hundred and sixty-four pregnant women aged 18-35 years, with uncomplicated pregnancies at gestational age ≥37 weeks to ≤40 weeks with premature rupture of membranes, were included. All primigravida and multiparous with previous normal vaginal deliveries were selected. Patients were selected with reactive CTG, adequate pelvis, clear liquor and vertex presentation. Induction of labour achieved with cervical Prostaglandin E2. Labour was monitored accordingly. Results: Seventy-four women (45%) presented (and got induction of labour) within 12 hours of premature rupture of membranes (early induction of labour), while 90(55%) fell under late induction of labour. 35(21%) were delivered by instrumental vaginal delivery, while 31(19%) were delivered by caesarian section. The most common indication of the caesarian section was fetal distress (36%), followed by poor progress of labour (32%). Patients with early induction of labour witnessed less chorioamnionitis (7% vs 18%) and post-partum haemorrhage (8% vs 13%). Likewise, with early induction of labour incidence of neonatal sepsis was less (3% vs 10%) with limited poor APGARs at birth (3% vs 12%). No early neonatal death was observed in 164 cases. Conclusion: For women with term premature rupture of membranes, earlier induction of labour results in lower maternal and fetal morbidity.
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spelling doaj.art-cbdd2960541c4bb59494119eb7dcf8c72023-01-31T08:19:45ZengArmy Medical College RawalpindiPakistan Armed Forces Medical Journal0030-96482411-88422023-01-0172610.51253/pafmj.v72i6.8164Outcome of Early and Late Induction of Labour in Premature Rupture of MembranesAmina Sohail0Mahum .1Tabassum Muzaffar2Uzma Saleem3Ali Mujtaba Tahir4Hafiz Zulqarnain5Combined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi PakistanKing Edward Medical University, Lahore PakistanCombined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi PakistanCombined Military Hospital, Kharian/National University of Medical Sciences (NUMS) PakistanCombined Military Hospital, Zhob/National University of Medical Sciences (NUMS) PakistanPak Emirates Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan Objective: To determine the frequency of early and late labour induction in premature rupture of membranes and compare their outcome. Study Design: Cross sectional study. Place and Duration of Study: Department of Obstetrics & Gynaecology, Combined Military Hospital, Rawalpindi Pakistan,from Jan-Dec 2021. Methodology: One hundred and sixty-four pregnant women aged 18-35 years, with uncomplicated pregnancies at gestational age ≥37 weeks to ≤40 weeks with premature rupture of membranes, were included. All primigravida and multiparous with previous normal vaginal deliveries were selected. Patients were selected with reactive CTG, adequate pelvis, clear liquor and vertex presentation. Induction of labour achieved with cervical Prostaglandin E2. Labour was monitored accordingly. Results: Seventy-four women (45%) presented (and got induction of labour) within 12 hours of premature rupture of membranes (early induction of labour), while 90(55%) fell under late induction of labour. 35(21%) were delivered by instrumental vaginal delivery, while 31(19%) were delivered by caesarian section. The most common indication of the caesarian section was fetal distress (36%), followed by poor progress of labour (32%). Patients with early induction of labour witnessed less chorioamnionitis (7% vs 18%) and post-partum haemorrhage (8% vs 13%). Likewise, with early induction of labour incidence of neonatal sepsis was less (3% vs 10%) with limited poor APGARs at birth (3% vs 12%). No early neonatal death was observed in 164 cases. Conclusion: For women with term premature rupture of membranes, earlier induction of labour results in lower maternal and fetal morbidity. https://pafmj.org/index.php/PAFMJ/article/view/8164Cesarean sectionChorioamnionitisInduction of labourNeonatal sepsisPremature rupture of membranesTerm gestation
spellingShingle Amina Sohail
Mahum .
Tabassum Muzaffar
Uzma Saleem
Ali Mujtaba Tahir
Hafiz Zulqarnain
Outcome of Early and Late Induction of Labour in Premature Rupture of Membranes
Pakistan Armed Forces Medical Journal
Cesarean section
Chorioamnionitis
Induction of labour
Neonatal sepsis
Premature rupture of membranes
Term gestation
title Outcome of Early and Late Induction of Labour in Premature Rupture of Membranes
title_full Outcome of Early and Late Induction of Labour in Premature Rupture of Membranes
title_fullStr Outcome of Early and Late Induction of Labour in Premature Rupture of Membranes
title_full_unstemmed Outcome of Early and Late Induction of Labour in Premature Rupture of Membranes
title_short Outcome of Early and Late Induction of Labour in Premature Rupture of Membranes
title_sort outcome of early and late induction of labour in premature rupture of membranes
topic Cesarean section
Chorioamnionitis
Induction of labour
Neonatal sepsis
Premature rupture of membranes
Term gestation
url https://pafmj.org/index.php/PAFMJ/article/view/8164
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AT tabassummuzaffar outcomeofearlyandlateinductionoflabourinprematureruptureofmembranes
AT uzmasaleem outcomeofearlyandlateinductionoflabourinprematureruptureofmembranes
AT alimujtabatahir outcomeofearlyandlateinductionoflabourinprematureruptureofmembranes
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