Changes in parameters of function of external respiration in patients with end stage of chronic kidney disease who are on substitution therapy.
The aim of our study was to evaluate the changes in the parameters of function of external respiration in patients with end-stage of chronic kidney disease after kidney transplantation in connection with chronic kidney disease under conditions of replacement therapy and compare with the results in p...
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| Format: | Article |
| Language: | English |
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Dnipro State Medical University
2018-10-01
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| Series: | Medičnì Perspektivi |
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| Online Access: | http://journals.uran.ua/index.php/2307-0404/article/view/142352 |
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| author | O. V. Kuryata O. O. Shtepa O. V. Halushchak |
| author_facet | O. V. Kuryata O. O. Shtepa O. V. Halushchak |
| author_sort | O. V. Kuryata |
| collection | DOAJ |
| description | The aim of our study was to evaluate the changes in the parameters of function of external respiration in patients with end-stage of chronic kidney disease after kidney transplantation in connection with chronic kidney disease under conditions of replacement therapy and compare with the results in patients after kidney transplantation. The first group included 40 patients with end-stage of chronic kidney disease under conditions of replacement dialysis therapy. The second group included 19 patients after kidney transplantation. A significant difference (p˂0,05) was found in patients of the first and second groups between the indicators of the FVC (90 [75-110]% и 98 [91-108]%), FEV1 (79 [71-93]% и 96 [84-104]%), PEF (61 [40-87]% и 82 [64-94]%), MEF 25-75 (52,5 [39-71]% и 80 [66-112]%). The indices of both groups were significantly lower relative to the comparison group: FVC (107,5 [105,5-124]%), FEV1 (100,5 [96-105,5]%), PEF (99,5 [95-102,5]%), MEF 25-75 (98,5 [97,5-101,5]%). In both groups, a statistically significant negative correlation was found between the indicators of the VCmax, FEV1, PEF, MEF 25-75 (R = -0,46, p <0,005; R = -0,43, p<0.05; R = -0,73, p <0,05; R = -0,41, p <0,05). Moderate decrease in the parameters of VCmax, FEV1, PEF, MEF 25-75 in patients with end-stage of chronic kidney disease requires monitoring of FVC with spirometry, especially in conditions of hemodialysis. |
| first_indexed | 2024-12-20T23:32:20Z |
| format | Article |
| id | doaj.art-cbdd5a2beef6452c8fa130759db8f905 |
| institution | Directory Open Access Journal |
| issn | 2307-0404 |
| language | English |
| last_indexed | 2024-12-20T23:32:20Z |
| publishDate | 2018-10-01 |
| publisher | Dnipro State Medical University |
| record_format | Article |
| series | Medičnì Perspektivi |
| spelling | doaj.art-cbdd5a2beef6452c8fa130759db8f9052022-12-21T19:23:17ZengDnipro State Medical UniversityMedičnì Perspektivi2307-04042018-10-01233(part1)13714210.26641/2307-0404.2018.3(part1).142352142352Changes in parameters of function of external respiration in patients with end stage of chronic kidney disease who are on substitution therapy.O. V. KuryataO. O. ShtepaO. V. HalushchakThe aim of our study was to evaluate the changes in the parameters of function of external respiration in patients with end-stage of chronic kidney disease after kidney transplantation in connection with chronic kidney disease under conditions of replacement therapy and compare with the results in patients after kidney transplantation. The first group included 40 patients with end-stage of chronic kidney disease under conditions of replacement dialysis therapy. The second group included 19 patients after kidney transplantation. A significant difference (p˂0,05) was found in patients of the first and second groups between the indicators of the FVC (90 [75-110]% и 98 [91-108]%), FEV1 (79 [71-93]% и 96 [84-104]%), PEF (61 [40-87]% и 82 [64-94]%), MEF 25-75 (52,5 [39-71]% и 80 [66-112]%). The indices of both groups were significantly lower relative to the comparison group: FVC (107,5 [105,5-124]%), FEV1 (100,5 [96-105,5]%), PEF (99,5 [95-102,5]%), MEF 25-75 (98,5 [97,5-101,5]%). In both groups, a statistically significant negative correlation was found between the indicators of the VCmax, FEV1, PEF, MEF 25-75 (R = -0,46, p <0,005; R = -0,43, p<0.05; R = -0,73, p <0,05; R = -0,41, p <0,05). Moderate decrease in the parameters of VCmax, FEV1, PEF, MEF 25-75 in patients with end-stage of chronic kidney disease requires monitoring of FVC with spirometry, especially in conditions of hemodialysis.http://journals.uran.ua/index.php/2307-0404/article/view/142352function of external respirationend-stage of chronic kidney diseasekidney transplantation |
| spellingShingle | O. V. Kuryata O. O. Shtepa O. V. Halushchak Changes in parameters of function of external respiration in patients with end stage of chronic kidney disease who are on substitution therapy. Medičnì Perspektivi function of external respiration end-stage of chronic kidney disease kidney transplantation |
| title | Changes in parameters of function of external respiration in patients with end stage of chronic kidney disease who are on substitution therapy. |
| title_full | Changes in parameters of function of external respiration in patients with end stage of chronic kidney disease who are on substitution therapy. |
| title_fullStr | Changes in parameters of function of external respiration in patients with end stage of chronic kidney disease who are on substitution therapy. |
| title_full_unstemmed | Changes in parameters of function of external respiration in patients with end stage of chronic kidney disease who are on substitution therapy. |
| title_short | Changes in parameters of function of external respiration in patients with end stage of chronic kidney disease who are on substitution therapy. |
| title_sort | changes in parameters of function of external respiration in patients with end stage of chronic kidney disease who are on substitution therapy |
| topic | function of external respiration end-stage of chronic kidney disease kidney transplantation |
| url | http://journals.uran.ua/index.php/2307-0404/article/view/142352 |
| work_keys_str_mv | AT ovkuryata changesinparametersoffunctionofexternalrespirationinpatientswithendstageofchronickidneydiseasewhoareonsubstitutiontherapy AT ooshtepa changesinparametersoffunctionofexternalrespirationinpatientswithendstageofchronickidneydiseasewhoareonsubstitutiontherapy AT ovhalushchak changesinparametersoffunctionofexternalrespirationinpatientswithendstageofchronickidneydiseasewhoareonsubstitutiontherapy |