Necrotic Cell Death and Inflammasome NLRP3 Activity in <i>Mycobacterium bovis</i>-Infected Bovine Macrophages

Necrotic Cell Death and Inflammasome NLRP3 Activity in <i>Mycobacterium bovis</i>-Infected Bovine Macrophages

<i>Mycobacterium bovis</i> is a facultative intracellular bacterium that produces cellular necrosis in granulomatous lesions in bovines. Although <i>M. bovis</i>-induced inflammation actively participates in granuloma development, its role in necrotic cell death and in bovine...

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Bibliographic Details
Main Authors: Omar Escobar-Chavarría, Alejandro Benitez-Guzman, Itzel Jiménez-Vázquez, Jacobo Carrisoza-Urbina, Lourdes Arriaga-Pizano, Sara Huerta-Yépez, Guillermina Baay-Guzmán, José A. Gutiérrez-Pabello
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Cells
Subjects:
bovine tuberculosis
inflammasome
cell death pathways
pyroptosis
ASC specks
caspase-1
Online Access:https://www.mdpi.com/2073-4409/12/16/2079

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