Effect of Carob Supplement on Spermogram Parameters and Sexual Function of Infertile Men Referred to the Infertility Center, Hamadan, Iran, 2019: A Randomized Controlled Trial
Objective: The purpose of this study is comparison of carob with placebo in the treatment of male infertility. Materials and methods: This study was performed as a clinical trial with two-group pretest-posttest design. Each group consisted of 30 members. The first group received 1.5 grams of carob...
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2023-09-01
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| Series: | Journal of Family and Reproductive Health |
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| Online Access: | https://jfrh.tums.ac.ir/index.php/jfrh/article/view/2331 |
| _version_ | 1797688850502385664 |
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| author | Shamim Pilehvari Tayebeh Gharakhani Bahar Seyedeh Zahra Masoumi Farideh Kazemi Shirin Moradkhani Alireza Rastgoo Haghi Parvin Maleki |
| author_facet | Shamim Pilehvari Tayebeh Gharakhani Bahar Seyedeh Zahra Masoumi Farideh Kazemi Shirin Moradkhani Alireza Rastgoo Haghi Parvin Maleki |
| author_sort | Shamim Pilehvari |
| collection | DOAJ |
| description |
Objective: The purpose of this study is comparison of carob with placebo in the treatment of male infertility.
Materials and methods: This study was performed as a clinical trial with two-group pretest-posttest design. Each group consisted of 30 members. The first group received 1.5 grams of carob per day, and the second group received placebo treatments. Treatment lasted for 12 weeks. Semen analysis as well as testosterone, prolactin, (LH), (FSH) and (TSH) were performed before and after drug treatment in two groups. Sexual function was assessed in the groups in two stages before and after the intervention using the standard International Index of Erectile Function. P-value less than 0.05 was considered statistically significant. Statistical analysis of data was performed using SPSS 16.
Results: The participants’ mean age was 34.83 ±6.22 in the placebo and 33.67 ±5.82 years in the Carob group. The results showed in the carob group compared to the placebo group, the rate of normal sperm counts increased by 17% and also the normal level of testosterone was 40% higher than the abnormal levels of the placebo group and these differences were statistically significant (P <0.05). And in most areas of sexual function, the mean scores after the intervention were higher than before (P> 0.05).
Conclusion: It is recommended to use carob supplements to improve spermogram parameters and male sex hormones.
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| format | Article |
| id | doaj.art-cbdf6b7e4c2144909341290f0ec7d015 |
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| issn | 1735-8949 1735-9392 |
| language | English |
| last_indexed | 2024-03-12T01:37:34Z |
| publishDate | 2023-09-01 |
| publisher | Tehran University of Medical Sciences |
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| series | Journal of Family and Reproductive Health |
| spelling | doaj.art-cbdf6b7e4c2144909341290f0ec7d0152023-09-11T05:13:05ZengTehran University of Medical SciencesJournal of Family and Reproductive Health1735-89491735-93922023-09-0117310.18502/jfrh.v17i3.13537Effect of Carob Supplement on Spermogram Parameters and Sexual Function of Infertile Men Referred to the Infertility Center, Hamadan, Iran, 2019: A Randomized Controlled TrialShamim Pilehvari0Tayebeh Gharakhani Bahar1Seyedeh Zahra Masoumi2Farideh Kazemi3Shirin Moradkhani4Alireza Rastgoo Haghi5Parvin Maleki6Endometrium and Endometriosis research center, Medicine school, Hamadan University of medical sciences, Hamadan, IranDepartment of Midwifery, Mother and Child Care Research Center, School of Nursing and Midwifery, Hamadan University of Medical Sciences, Hamadan, IranDepartment of Midwifery, Mother and Child Care Research Center, School of Nursing and Midwifery, Hamadan University of Medical Sciences, Hamadan, IranDepartment of Midwifery, Mother and Child Care Research Center, School of Nursing and Midwifery, Hamadan University of Medical Sciences, Hamadan, IranDepartment of Pharmacognosy, School of Pharmacy, Hamadan University of Medical Sciences, Hamadan, Iran AND Medicinal Plants and Natural Products Research Center, Hamadan University of Medical Sciences, Hamadan, IranDepartment of Pathology, Medicine school, Hamadan University of medical sciences, Hamadan, IranDepartment of Midwifery, Mother and Child Care Research Center, School of Nursing and Midwifery, Hamadan University of Medical Sciences, Hamadan, Iran Objective: The purpose of this study is comparison of carob with placebo in the treatment of male infertility. Materials and methods: This study was performed as a clinical trial with two-group pretest-posttest design. Each group consisted of 30 members. The first group received 1.5 grams of carob per day, and the second group received placebo treatments. Treatment lasted for 12 weeks. Semen analysis as well as testosterone, prolactin, (LH), (FSH) and (TSH) were performed before and after drug treatment in two groups. Sexual function was assessed in the groups in two stages before and after the intervention using the standard International Index of Erectile Function. P-value less than 0.05 was considered statistically significant. Statistical analysis of data was performed using SPSS 16. Results: The participants’ mean age was 34.83 ±6.22 in the placebo and 33.67 ±5.82 years in the Carob group. The results showed in the carob group compared to the placebo group, the rate of normal sperm counts increased by 17% and also the normal level of testosterone was 40% higher than the abnormal levels of the placebo group and these differences were statistically significant (P <0.05). And in most areas of sexual function, the mean scores after the intervention were higher than before (P> 0.05). Conclusion: It is recommended to use carob supplements to improve spermogram parameters and male sex hormones. https://jfrh.tums.ac.ir/index.php/jfrh/article/view/2331CarobClinical TrialMale InfertilitySexual Dysfunction |
| spellingShingle | Shamim Pilehvari Tayebeh Gharakhani Bahar Seyedeh Zahra Masoumi Farideh Kazemi Shirin Moradkhani Alireza Rastgoo Haghi Parvin Maleki Effect of Carob Supplement on Spermogram Parameters and Sexual Function of Infertile Men Referred to the Infertility Center, Hamadan, Iran, 2019: A Randomized Controlled Trial Journal of Family and Reproductive Health Carob Clinical Trial Male Infertility Sexual Dysfunction |
| title | Effect of Carob Supplement on Spermogram Parameters and Sexual Function of Infertile Men Referred to the Infertility Center, Hamadan, Iran, 2019: A Randomized Controlled Trial |
| title_full | Effect of Carob Supplement on Spermogram Parameters and Sexual Function of Infertile Men Referred to the Infertility Center, Hamadan, Iran, 2019: A Randomized Controlled Trial |
| title_fullStr | Effect of Carob Supplement on Spermogram Parameters and Sexual Function of Infertile Men Referred to the Infertility Center, Hamadan, Iran, 2019: A Randomized Controlled Trial |
| title_full_unstemmed | Effect of Carob Supplement on Spermogram Parameters and Sexual Function of Infertile Men Referred to the Infertility Center, Hamadan, Iran, 2019: A Randomized Controlled Trial |
| title_short | Effect of Carob Supplement on Spermogram Parameters and Sexual Function of Infertile Men Referred to the Infertility Center, Hamadan, Iran, 2019: A Randomized Controlled Trial |
| title_sort | effect of carob supplement on spermogram parameters and sexual function of infertile men referred to the infertility center hamadan iran 2019 a randomized controlled trial |
| topic | Carob Clinical Trial Male Infertility Sexual Dysfunction |
| url | https://jfrh.tums.ac.ir/index.php/jfrh/article/view/2331 |
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