Interactive registration of 2D histology and 3D CT data for assessment of radiofrequency ablation treatment
Histological investigation of a lesion induced by radiofrequency ablation (RFA) treatment provides ground-truth about the true lesion size, thus verifying the success or failure of the RFA treatment. This work presents a framework for registration of two-dimensional large-scale histological sections...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2011-01-01
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| Series: | Journal of Pathology Informatics |
| Subjects: | |
| Online Access: | http://www.jpathinformatics.org/article.asp?issn=2153-3539;year=2011;volume=2;issue=2;spage=9;epage=9;aulast=Seise |
| _version_ | 1811244714753523712 |
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| author | Matthias Seise Tuomas Alhonnoro Marina Kolesnik |
| author_facet | Matthias Seise Tuomas Alhonnoro Marina Kolesnik |
| author_sort | Matthias Seise |
| collection | DOAJ |
| description | Histological investigation of a lesion induced by radiofrequency ablation (RFA) treatment provides ground-truth about the true lesion size, thus verifying the success or failure of the RFA treatment. This work presents a framework for registration of two-dimensional large-scale histological sections and three-dimensional CT data typically used to guide the RFA intervention. The focus is on the developed interactive methods for reconstruction of the histological volume data by fusion of histological and high-resolution CT (MicroCT) data and registration into CT data based on natural feature points. The framework is evaluated using RFA interventions in a porcine liver and applying medically relevant metrics. The results of registration are within clinically required precision targets; thus the developed methods are suitable for validation of the RFA treatment. |
| first_indexed | 2024-04-12T14:30:01Z |
| format | Article |
| id | doaj.art-cbe33643006a4844ba67157fdc20f5c2 |
| institution | Directory Open Access Journal |
| issn | 2153-3539 2153-3539 |
| language | English |
| last_indexed | 2024-04-12T14:30:01Z |
| publishDate | 2011-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Pathology Informatics |
| spelling | doaj.art-cbe33643006a4844ba67157fdc20f5c22022-12-22T03:29:19ZengElsevierJournal of Pathology Informatics2153-35392153-35392011-01-01229910.4103/2153-3539.92036Interactive registration of 2D histology and 3D CT data for assessment of radiofrequency ablation treatmentMatthias SeiseTuomas AlhonnoroMarina KolesnikHistological investigation of a lesion induced by radiofrequency ablation (RFA) treatment provides ground-truth about the true lesion size, thus verifying the success or failure of the RFA treatment. This work presents a framework for registration of two-dimensional large-scale histological sections and three-dimensional CT data typically used to guide the RFA intervention. The focus is on the developed interactive methods for reconstruction of the histological volume data by fusion of histological and high-resolution CT (MicroCT) data and registration into CT data based on natural feature points. The framework is evaluated using RFA interventions in a porcine liver and applying medically relevant metrics. The results of registration are within clinically required precision targets; thus the developed methods are suitable for validation of the RFA treatment.http://www.jpathinformatics.org/article.asp?issn=2153-3539;year=2011;volume=2;issue=2;spage=9;epage=9;aulast=SeiseHistology imagingCT/MicroCT data2D-3D registrationthin-plate-spline registrationradio frequency ablation |
| spellingShingle | Matthias Seise Tuomas Alhonnoro Marina Kolesnik Interactive registration of 2D histology and 3D CT data for assessment of radiofrequency ablation treatment Journal of Pathology Informatics Histology imaging CT/MicroCT data 2D-3D registration thin-plate-spline registration radio frequency ablation |
| title | Interactive registration of 2D histology and 3D CT data for assessment of radiofrequency ablation treatment |
| title_full | Interactive registration of 2D histology and 3D CT data for assessment of radiofrequency ablation treatment |
| title_fullStr | Interactive registration of 2D histology and 3D CT data for assessment of radiofrequency ablation treatment |
| title_full_unstemmed | Interactive registration of 2D histology and 3D CT data for assessment of radiofrequency ablation treatment |
| title_short | Interactive registration of 2D histology and 3D CT data for assessment of radiofrequency ablation treatment |
| title_sort | interactive registration of 2d histology and 3d ct data for assessment of radiofrequency ablation treatment |
| topic | Histology imaging CT/MicroCT data 2D-3D registration thin-plate-spline registration radio frequency ablation |
| url | http://www.jpathinformatics.org/article.asp?issn=2153-3539;year=2011;volume=2;issue=2;spage=9;epage=9;aulast=Seise |
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