Role of Ionizing Radiation in Neurodegenerative Diseases
Ionizing radiation (IR) from terrestrial sources is continually an unprotected peril to human beings. However, the medical radiation and global radiation background are main contributors to human exposure and causes of radiation sickness. At high-dose exposures acute radiation sickness occurs, where...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2018-05-01
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| Series: | Frontiers in Aging Neuroscience |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/article/10.3389/fnagi.2018.00134/full |
| _version_ | 1811212436185808896 |
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| author | Neel K. Sharma Rupali Sharma Deepali Mathur Shashwat Sharad Gillipsie Minhas Kulsajan Bhatia Akshay Anand Sanchita P. Ghosh |
| author_facet | Neel K. Sharma Rupali Sharma Deepali Mathur Shashwat Sharad Gillipsie Minhas Kulsajan Bhatia Akshay Anand Sanchita P. Ghosh |
| author_sort | Neel K. Sharma |
| collection | DOAJ |
| description | Ionizing radiation (IR) from terrestrial sources is continually an unprotected peril to human beings. However, the medical radiation and global radiation background are main contributors to human exposure and causes of radiation sickness. At high-dose exposures acute radiation sickness occurs, whereas chronic effects may persist for a number of years. Radiation can increase many circulatory, age related and neurodegenerative diseases. Neurodegenerative diseases occur a long time after exposure to radiation, as demonstrated in atomic bomb survivors, and are still controversial. This review discuss the role of IR in neurodegenerative diseases and proposes an association between neurodegenerative diseases and exposure to IR. |
| first_indexed | 2024-04-12T05:29:23Z |
| format | Article |
| id | doaj.art-cbe3db9ce6b54144892da3c0cb03cf95 |
| institution | Directory Open Access Journal |
| issn | 1663-4365 |
| language | English |
| last_indexed | 2024-04-12T05:29:23Z |
| publishDate | 2018-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Aging Neuroscience |
| spelling | doaj.art-cbe3db9ce6b54144892da3c0cb03cf952022-12-22T03:46:10ZengFrontiers Media S.A.Frontiers in Aging Neuroscience1663-43652018-05-011010.3389/fnagi.2018.00134296161Role of Ionizing Radiation in Neurodegenerative DiseasesNeel K. Sharma0Rupali Sharma1Deepali Mathur2Shashwat Sharad3Gillipsie Minhas4Kulsajan Bhatia5Akshay Anand6Sanchita P. Ghosh7Armed Forces Radiobiology Research Institute, Uniformed Services University of the Health Sciences, Bethesda, MD, United StatesCenter for Neuroscience and Regenerative Medicine, Department of Pathology, Uniformed Services University of the Health Sciences, Bethesda, MD, United StatesNeurobiology Laboratory, School of Biotechnology, KIIT University, Bhubaneswar, IndiaCenter for Prostate Disease Research, Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD, United StatesNeuroscience Research Lab, Department of Neurology, Postgraduate Institute of Medical Education & Research (PGIMER), Chandigarh, IndiaGovernment Medical College and Hospital, Chandigarh, IndiaNeuroscience Research Lab, Department of Neurology, Postgraduate Institute of Medical Education & Research (PGIMER), Chandigarh, IndiaArmed Forces Radiobiology Research Institute, Uniformed Services University of the Health Sciences, Bethesda, MD, United StatesIonizing radiation (IR) from terrestrial sources is continually an unprotected peril to human beings. However, the medical radiation and global radiation background are main contributors to human exposure and causes of radiation sickness. At high-dose exposures acute radiation sickness occurs, whereas chronic effects may persist for a number of years. Radiation can increase many circulatory, age related and neurodegenerative diseases. Neurodegenerative diseases occur a long time after exposure to radiation, as demonstrated in atomic bomb survivors, and are still controversial. This review discuss the role of IR in neurodegenerative diseases and proposes an association between neurodegenerative diseases and exposure to IR.http://journal.frontiersin.org/article/10.3389/fnagi.2018.00134/fullionizing radiationhypoxiaagingneurodegenerative diseasesCNS |
| spellingShingle | Neel K. Sharma Rupali Sharma Deepali Mathur Shashwat Sharad Gillipsie Minhas Kulsajan Bhatia Akshay Anand Sanchita P. Ghosh Role of Ionizing Radiation in Neurodegenerative Diseases Frontiers in Aging Neuroscience ionizing radiation hypoxia aging neurodegenerative diseases CNS |
| title | Role of Ionizing Radiation in Neurodegenerative Diseases |
| title_full | Role of Ionizing Radiation in Neurodegenerative Diseases |
| title_fullStr | Role of Ionizing Radiation in Neurodegenerative Diseases |
| title_full_unstemmed | Role of Ionizing Radiation in Neurodegenerative Diseases |
| title_short | Role of Ionizing Radiation in Neurodegenerative Diseases |
| title_sort | role of ionizing radiation in neurodegenerative diseases |
| topic | ionizing radiation hypoxia aging neurodegenerative diseases CNS |
| url | http://journal.frontiersin.org/article/10.3389/fnagi.2018.00134/full |
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