Chromatin Interaction Changes during the iPSC-NPC Model to Facilitate the Study of Biologically Significant Genes Involved in Differentiation

Chromatin Interaction Changes during the iPSC-NPC Model to Facilitate the Study of Biologically Significant Genes Involved in Differentiation

Given the difficulties of obtaining diseased cells, differentiation of neurons from patient-specific human induced pluripotent stem cells (iPSCs) with neural progenitor cells (NPCs) as intermediate precursors is of great interest. While cellular and transcriptomic changes during the differentiation...

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Bibliographic Details
Main Authors: Won-Young Choi, Ji-Hyun Hwang, Jin-Young Lee, Ann-Na Cho, Andrew J Lee, Inkyung Jung, Seung-Woo Cho, Lark Kyun Kim, Young-Joon Kim
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Genes
Subjects:
Hi-C
spatial organization
chromatin interactions
human induced pluripotent stem cells
neural progenitor cells
neuronal differentiation
Online Access:https://www.mdpi.com/2073-4425/11/10/1176

Internet

https://www.mdpi.com/2073-4425/11/10/1176

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