Metabolic Remodeling in the Pressure‐Loaded Right Ventricle: Shifts in Glucose and Fatty Acid Metabolism—A Systematic Review and Meta‐Analysis

Metabolic Remodeling in the Pressure‐Loaded Right Ventricle: Shifts in Glucose and Fatty Acid Metabolism—A Systematic Review and Meta‐Analysis

Background Right ventricular (RV) failure because of chronic pressure load is an important determinant of outcome in pulmonary hypertension. Progression towards RV failure is characterized by diastolic dysfunction, fibrosis and metabolic dysregulation. Metabolic modulation has been suggested as ther...

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Bibliographic Details
Main Authors: Anne‐Marie C. Koop, Guido P. L. Bossers, Mark‐Jan Ploegstra, Quint A. J. Hagdorn, Rolf M. F. Berger, Herman H. W. Silljé, Beatrijs Bartelds
Format: Article
Language:English
Published: Wiley 2019-11-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
heart failure
metabolism
myocardial biology
pulmonary hypertension
remodeling
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.119.012086

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.119.012086

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