The mechanical properties and bioactivity of Ti–Mg composites as orthopedic implants: A pilot study

Stress shielding effects and bioinertia are two main problems of titanium alloy orthopedic implants, which are commonly used in clinical therapy. By adjusting the porosity of the Ti alloy, the stress shielding effects can be avoided and the strength of the titanium alloy is also significantly decrea...

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Main Authors: Lei Miao, Ming Gao, Siying Chen, Jinhe Wang, Haifeng Zhang, Lili Tan, Yaping Pan
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Journal of Materials Research and Technology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2238785423031320
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author Lei Miao
Ming Gao
Siying Chen
Jinhe Wang
Haifeng Zhang
Lili Tan
Yaping Pan
author_facet Lei Miao
Ming Gao
Siying Chen
Jinhe Wang
Haifeng Zhang
Lili Tan
Yaping Pan
author_sort Lei Miao
collection DOAJ
description Stress shielding effects and bioinertia are two main problems of titanium alloy orthopedic implants, which are commonly used in clinical therapy. By adjusting the porosity of the Ti alloy, the stress shielding effects can be avoided and the strength of the titanium alloy is also significantly decreased. To improve the mechanical property and bioactivity, Ti–Mg composites were fabricated by pressureless infiltration and 3D printed. Excellent mechanical properties, biocompatibility and bioactivity of the Ti–Mg composites were demonstrated by in vitro and in vivo results. The ultimate compressive strength and compressive yield strength could be increased to 292.5 ± 10.0 MPa and 27.9 % 220.0 ± 11.5 MPa, respectively. Furthermore, the bioactivity of Ti–Mg composites was also significantly improved due to the release of Mg ions during the degradation process, which can promote osteoblast adhesion and differentiation.
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spelling doaj.art-cbeb8b602c1945b785049411aa27e24f2024-01-31T05:43:29ZengElsevierJournal of Materials Research and Technology2238-78542024-01-012810741083The mechanical properties and bioactivity of Ti–Mg composites as orthopedic implants: A pilot studyLei Miao0Ming Gao1Siying Chen2Jinhe Wang3Haifeng Zhang4Lili Tan5Yaping Pan6Department of Periodontics, School and Hospital of Stomatology, China Medical University, Liaoning Provincial Key Laboratory of Oral Diseases, Shenyang, 110000, ChinaInstitute of Metal Research, Chinese Academy of Sciences, Shenyang, 110016, ChinaDepartment of Periodontics, School and Hospital of Stomatology, China Medical University, Liaoning Provincial Key Laboratory of Oral Diseases, Shenyang, 110000, ChinaInstitute of Metal Research, Chinese Academy of Sciences, Shenyang, 110016, ChinaInstitute of Metal Research, Chinese Academy of Sciences, Shenyang, 110016, ChinaInstitute of Metal Research, Chinese Academy of Sciences, Shenyang, 110016, China; Corresponding author.Department of Periodontics, School and Hospital of Stomatology, China Medical University, Liaoning Provincial Key Laboratory of Oral Diseases, Shenyang, 110000, China; Corresponding author.Stress shielding effects and bioinertia are two main problems of titanium alloy orthopedic implants, which are commonly used in clinical therapy. By adjusting the porosity of the Ti alloy, the stress shielding effects can be avoided and the strength of the titanium alloy is also significantly decreased. To improve the mechanical property and bioactivity, Ti–Mg composites were fabricated by pressureless infiltration and 3D printed. Excellent mechanical properties, biocompatibility and bioactivity of the Ti–Mg composites were demonstrated by in vitro and in vivo results. The ultimate compressive strength and compressive yield strength could be increased to 292.5 ± 10.0 MPa and 27.9 % 220.0 ± 11.5 MPa, respectively. Furthermore, the bioactivity of Ti–Mg composites was also significantly improved due to the release of Mg ions during the degradation process, which can promote osteoblast adhesion and differentiation.http://www.sciencedirect.com/science/article/pii/S2238785423031320Ti-Mg compositesMechanical propertiesCorrosionBioactivity
spellingShingle Lei Miao
Ming Gao
Siying Chen
Jinhe Wang
Haifeng Zhang
Lili Tan
Yaping Pan
The mechanical properties and bioactivity of Ti–Mg composites as orthopedic implants: A pilot study
Journal of Materials Research and Technology
Ti-Mg composites
Mechanical properties
Corrosion
Bioactivity
title The mechanical properties and bioactivity of Ti–Mg composites as orthopedic implants: A pilot study
title_full The mechanical properties and bioactivity of Ti–Mg composites as orthopedic implants: A pilot study
title_fullStr The mechanical properties and bioactivity of Ti–Mg composites as orthopedic implants: A pilot study
title_full_unstemmed The mechanical properties and bioactivity of Ti–Mg composites as orthopedic implants: A pilot study
title_short The mechanical properties and bioactivity of Ti–Mg composites as orthopedic implants: A pilot study
title_sort mechanical properties and bioactivity of ti mg composites as orthopedic implants a pilot study
topic Ti-Mg composites
Mechanical properties
Corrosion
Bioactivity
url http://www.sciencedirect.com/science/article/pii/S2238785423031320
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