The mechanical properties and bioactivity of Ti–Mg composites as orthopedic implants: A pilot study
Stress shielding effects and bioinertia are two main problems of titanium alloy orthopedic implants, which are commonly used in clinical therapy. By adjusting the porosity of the Ti alloy, the stress shielding effects can be avoided and the strength of the titanium alloy is also significantly decrea...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
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Elsevier
2024-01-01
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Series: | Journal of Materials Research and Technology |
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Online Access: | http://www.sciencedirect.com/science/article/pii/S2238785423031320 |
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author | Lei Miao Ming Gao Siying Chen Jinhe Wang Haifeng Zhang Lili Tan Yaping Pan |
author_facet | Lei Miao Ming Gao Siying Chen Jinhe Wang Haifeng Zhang Lili Tan Yaping Pan |
author_sort | Lei Miao |
collection | DOAJ |
description | Stress shielding effects and bioinertia are two main problems of titanium alloy orthopedic implants, which are commonly used in clinical therapy. By adjusting the porosity of the Ti alloy, the stress shielding effects can be avoided and the strength of the titanium alloy is also significantly decreased. To improve the mechanical property and bioactivity, Ti–Mg composites were fabricated by pressureless infiltration and 3D printed. Excellent mechanical properties, biocompatibility and bioactivity of the Ti–Mg composites were demonstrated by in vitro and in vivo results. The ultimate compressive strength and compressive yield strength could be increased to 292.5 ± 10.0 MPa and 27.9 % 220.0 ± 11.5 MPa, respectively. Furthermore, the bioactivity of Ti–Mg composites was also significantly improved due to the release of Mg ions during the degradation process, which can promote osteoblast adhesion and differentiation. |
first_indexed | 2024-03-08T09:29:12Z |
format | Article |
id | doaj.art-cbeb8b602c1945b785049411aa27e24f |
institution | Directory Open Access Journal |
issn | 2238-7854 |
language | English |
last_indexed | 2024-03-08T09:29:12Z |
publishDate | 2024-01-01 |
publisher | Elsevier |
record_format | Article |
series | Journal of Materials Research and Technology |
spelling | doaj.art-cbeb8b602c1945b785049411aa27e24f2024-01-31T05:43:29ZengElsevierJournal of Materials Research and Technology2238-78542024-01-012810741083The mechanical properties and bioactivity of Ti–Mg composites as orthopedic implants: A pilot studyLei Miao0Ming Gao1Siying Chen2Jinhe Wang3Haifeng Zhang4Lili Tan5Yaping Pan6Department of Periodontics, School and Hospital of Stomatology, China Medical University, Liaoning Provincial Key Laboratory of Oral Diseases, Shenyang, 110000, ChinaInstitute of Metal Research, Chinese Academy of Sciences, Shenyang, 110016, ChinaDepartment of Periodontics, School and Hospital of Stomatology, China Medical University, Liaoning Provincial Key Laboratory of Oral Diseases, Shenyang, 110000, ChinaInstitute of Metal Research, Chinese Academy of Sciences, Shenyang, 110016, ChinaInstitute of Metal Research, Chinese Academy of Sciences, Shenyang, 110016, ChinaInstitute of Metal Research, Chinese Academy of Sciences, Shenyang, 110016, China; Corresponding author.Department of Periodontics, School and Hospital of Stomatology, China Medical University, Liaoning Provincial Key Laboratory of Oral Diseases, Shenyang, 110000, China; Corresponding author.Stress shielding effects and bioinertia are two main problems of titanium alloy orthopedic implants, which are commonly used in clinical therapy. By adjusting the porosity of the Ti alloy, the stress shielding effects can be avoided and the strength of the titanium alloy is also significantly decreased. To improve the mechanical property and bioactivity, Ti–Mg composites were fabricated by pressureless infiltration and 3D printed. Excellent mechanical properties, biocompatibility and bioactivity of the Ti–Mg composites were demonstrated by in vitro and in vivo results. The ultimate compressive strength and compressive yield strength could be increased to 292.5 ± 10.0 MPa and 27.9 % 220.0 ± 11.5 MPa, respectively. Furthermore, the bioactivity of Ti–Mg composites was also significantly improved due to the release of Mg ions during the degradation process, which can promote osteoblast adhesion and differentiation.http://www.sciencedirect.com/science/article/pii/S2238785423031320Ti-Mg compositesMechanical propertiesCorrosionBioactivity |
spellingShingle | Lei Miao Ming Gao Siying Chen Jinhe Wang Haifeng Zhang Lili Tan Yaping Pan The mechanical properties and bioactivity of Ti–Mg composites as orthopedic implants: A pilot study Journal of Materials Research and Technology Ti-Mg composites Mechanical properties Corrosion Bioactivity |
title | The mechanical properties and bioactivity of Ti–Mg composites as orthopedic implants: A pilot study |
title_full | The mechanical properties and bioactivity of Ti–Mg composites as orthopedic implants: A pilot study |
title_fullStr | The mechanical properties and bioactivity of Ti–Mg composites as orthopedic implants: A pilot study |
title_full_unstemmed | The mechanical properties and bioactivity of Ti–Mg composites as orthopedic implants: A pilot study |
title_short | The mechanical properties and bioactivity of Ti–Mg composites as orthopedic implants: A pilot study |
title_sort | mechanical properties and bioactivity of ti mg composites as orthopedic implants a pilot study |
topic | Ti-Mg composites Mechanical properties Corrosion Bioactivity |
url | http://www.sciencedirect.com/science/article/pii/S2238785423031320 |
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