Age-dependent changes in circulating Tfh cells influence development of functional malaria antibodies in children
Despite being key drivers of protective antibodies against malaria, little is known regarding the host and parasite factors that influence CD4 T-follicular helper cell and antibody development. Authors utilise samples from a study of children living in an area of high malaria transmission in Uganda,...
Հիմնական հեղինակներ: | Jo-Anne Chan, Jessica R. Loughland, Lauren de la Parte, Satomi Okano, Isaac Ssewanyana, Mayimuna Nalubega, Felistas Nankya, Kenneth Musinguzi, John Rek, Emmanuel Arinaitwe, Peta Tipping, Peter Bourke, Dean Andrew, Nicholas Dooley, Arya SheelaNair, Bruce D. Wines, P. Mark Hogarth, James G. Beeson, Bryan Greenhouse, Grant Dorsey, Moses Kamya, Gunter Hartel, Gabriela Minigo, Margaret Feeney, Prasanna Jagannathan, Michelle J. Boyle |
---|---|
Ձևաչափ: | Հոդված |
Լեզու: | English |
Հրապարակվել է: |
Nature Portfolio
2022-07-01
|
Շարք: | Nature Communications |
Առցանց հասանելիություն: | https://doi.org/10.1038/s41467-022-31880-6 |
Նմանատիպ նյութեր
-
Opsonized antigen activates Vδ2+ T cells via CD16/FCγRIIIa in individuals with chronic malaria exposure.
: Lila A Farrington, և այլն
Հրապարակվել է: (2020-10-01) -
Exposure to pesticides in utero impacts the fetal immune system and response to vaccination in infancy
: Mary Prahl, և այլն
Հրապարակվել է: (2021-01-01) -
Decline of FoxP3+ Regulatory CD4 T Cells in Peripheral Blood of Children Heavily Exposed to Malaria.
: Michelle J Boyle, և այլն
Հրապարակվել է: (2015-07-01) -
The Development of Plasmodium falciparum-Specific IL10 CD4 T Cells and Protection from Malaria in Children in an Area of High Malaria Transmission
: Michelle J. Boyle, և այլն
Հրապարակվել է: (2017-10-01) -
Impact of a Rapid Decline in Malaria Transmission on Antimalarial IgG Subclasses and Avidity
: Isaac Ssewanyana, և այլն
Հրապարակվել է: (2021-01-01)