Comparison of the severity of cytopenias with etiologic factors in patients with pancytopenia and bicytopenia
INTRODUCTION: The aim of this study was to evaluate the severity of hematological findings according to etiology in patients with pancytopenia and bisitopenia. METHODS: patients with bicytopenia and pancytopenia who were examined in Diyarbakir Children Hospital Pediatric Hematology and Oncology clin...
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| Format: | Article |
| Language: | English |
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The Pan African Medical Journal
2019-11-01
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| Series: | The Pan African Medical Journal |
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https://www.panafrican-med-journal.com/content/article/34/149/pdf/149.pdf
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| _version_ | 1818910218111680512 |
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| author | Hakan Sarbay |
| author_facet | Hakan Sarbay |
| author_sort | Hakan Sarbay |
| collection | DOAJ |
| description | INTRODUCTION: The aim of this study was to evaluate the severity of hematological findings according to etiology in patients with pancytopenia and bisitopenia. METHODS: patients with bicytopenia and pancytopenia who were examined in Diyarbakir Children Hospital Pediatric Hematology and Oncology clinic between June 2017-June 2018 were evaluated retrospectively. RESULTS: of the 130 patients included in the study, 73 (56.2%) were male and 43 (43.8%) were female. The mean age of the patients was 4.9 , 4.86. 45 (34.6%) patients had pancytopenia and 85 (65.3%) had bicytopenia. The youngest patient was 1-month old and the oldest patient was 18-year-old. The mean blood count parameters were WBC: 10.207 , 39.781, neutrophil: 1515 , 1418, hgb: 9.3 , 2.3, MCV: 80 , 13.1, platelet: 118.823 , 93.645. Three out of 130 patients had hyperleucocytosis (WBC = 50.000/mm3). Vitamin B12 deficiency was detected in 35 patients. When patients with primary hematological disease were compared with patients with secondary causes of cytopenias, a significant difference was found in terms of leukocyte count, hemoglobin level, MCV elevation, and low platelet count. CONCLUSION: the determination of the severity of cytopenias in differential diagnosis may be useful in distinguishing primary hematological diseases from secondary causes of pancytopenia and bicytopenia. However, vitamin B12 deficiency in developing countries is one of the most important causes of public health as well as in the etiology of pancytopenia and bicytopenia. |
| first_indexed | 2024-12-19T22:39:18Z |
| format | Article |
| id | doaj.art-cbf1ab23f9ab4e09b002cc51377eaaab |
| institution | Directory Open Access Journal |
| issn | 1937-8688 1937-8688 |
| language | English |
| last_indexed | 2024-12-19T22:39:18Z |
| publishDate | 2019-11-01 |
| publisher | The Pan African Medical Journal |
| record_format | Article |
| series | The Pan African Medical Journal |
| spelling | doaj.art-cbf1ab23f9ab4e09b002cc51377eaaab2022-12-21T20:03:07ZengThe Pan African Medical JournalThe Pan African Medical Journal1937-86881937-86882019-11-013414910.11604/pamj.2019.34.149.1874918749Comparison of the severity of cytopenias with etiologic factors in patients with pancytopenia and bicytopeniaHakan SarbayINTRODUCTION: The aim of this study was to evaluate the severity of hematological findings according to etiology in patients with pancytopenia and bisitopenia. METHODS: patients with bicytopenia and pancytopenia who were examined in Diyarbakir Children Hospital Pediatric Hematology and Oncology clinic between June 2017-June 2018 were evaluated retrospectively. RESULTS: of the 130 patients included in the study, 73 (56.2%) were male and 43 (43.8%) were female. The mean age of the patients was 4.9 , 4.86. 45 (34.6%) patients had pancytopenia and 85 (65.3%) had bicytopenia. The youngest patient was 1-month old and the oldest patient was 18-year-old. The mean blood count parameters were WBC: 10.207 , 39.781, neutrophil: 1515 , 1418, hgb: 9.3 , 2.3, MCV: 80 , 13.1, platelet: 118.823 , 93.645. Three out of 130 patients had hyperleucocytosis (WBC = 50.000/mm3). Vitamin B12 deficiency was detected in 35 patients. When patients with primary hematological disease were compared with patients with secondary causes of cytopenias, a significant difference was found in terms of leukocyte count, hemoglobin level, MCV elevation, and low platelet count. CONCLUSION: the determination of the severity of cytopenias in differential diagnosis may be useful in distinguishing primary hematological diseases from secondary causes of pancytopenia and bicytopenia. However, vitamin B12 deficiency in developing countries is one of the most important causes of public health as well as in the etiology of pancytopenia and bicytopenia. https://www.panafrican-med-journal.com/content/article/34/149/pdf/149.pdf pancytopeniabicytopeniachildren |
| spellingShingle | Hakan Sarbay Comparison of the severity of cytopenias with etiologic factors in patients with pancytopenia and bicytopenia The Pan African Medical Journal pancytopenia bicytopenia children |
| title | Comparison of the severity of cytopenias with etiologic factors in patients with pancytopenia and bicytopenia |
| title_full | Comparison of the severity of cytopenias with etiologic factors in patients with pancytopenia and bicytopenia |
| title_fullStr | Comparison of the severity of cytopenias with etiologic factors in patients with pancytopenia and bicytopenia |
| title_full_unstemmed | Comparison of the severity of cytopenias with etiologic factors in patients with pancytopenia and bicytopenia |
| title_short | Comparison of the severity of cytopenias with etiologic factors in patients with pancytopenia and bicytopenia |
| title_sort | comparison of the severity of cytopenias with etiologic factors in patients with pancytopenia and bicytopenia |
| topic | pancytopenia bicytopenia children |
| url |
https://www.panafrican-med-journal.com/content/article/34/149/pdf/149.pdf
|
| work_keys_str_mv | AT hakansarbay comparisonoftheseverityofcytopeniaswithetiologicfactorsinpatientswithpancytopeniaandbicytopenia |