The Emerging Role of Nutrition in Parkinson’s disease

Typically, Parkinson’s disease (PD) is the second most prevalent neurodegenerative disease in ageing individuals. It is now clear that genetic susceptibility and environmental factors play a role in disease etiology and progression. Because environmental factors are involved with the majority of the...

Full description

Bibliographic Details
Main Authors: Stacey E Seidl, Jose A Santiago, Hope eBilyk, Judith A Potashkin
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-03-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2014.00036/full
Description
Summary:Typically, Parkinson’s disease (PD) is the second most prevalent neurodegenerative disease in ageing individuals. It is now clear that genetic susceptibility and environmental factors play a role in disease etiology and progression. Because environmental factors are involved with the majority of the cases of PD, it is important to understand the role nutrition plays in both neuroprotection and neurodegeneration. Recent epidemiological studies have revealed the promise of some nutrients in reducing the risk of PD since their intake is related to improvement of cognition and motor symptoms. In contrast, other nutrients may be involved with the etiology of neurodegeneration or exacerbate disease progression. This review summarizes the studies that have addressed these issues and describes in detail the nutrients and their putative mechanisms of action in PD.
ISSN:1663-4365