New Insights into Cellular Impacts of Metals in Aquatic Animals
Toxic metals remain a current important threat to aquatic ecosystems, despite regulatory efforts to reduce their release. Several toxic metals already appear in the list of priority substances polluting surface waters, while concerns arise from the increasing use of technology-critical metals such a...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-06-01
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| Series: | Environments |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-3298/7/6/46 |
| _version_ | 1797565191027687424 |
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| author | Aimie Le Saux Elise David Stéphane Betoulle Florence Bultelle Béatrice Rocher Iris Barjhoux Claudia Cosio |
| author_facet | Aimie Le Saux Elise David Stéphane Betoulle Florence Bultelle Béatrice Rocher Iris Barjhoux Claudia Cosio |
| author_sort | Aimie Le Saux |
| collection | DOAJ |
| description | Toxic metals remain a current important threat to aquatic ecosystems, despite regulatory efforts to reduce their release. Several toxic metals already appear in the list of priority substances polluting surface waters, while concerns arise from the increasing use of technology-critical metals such as metallic nanoparticles, rare-earth, and platinum group metals. In aquatic environments, various chemical, biological and physical processes determine the impact of metals on the biota. This review provides insights into responses to toxic metals recently reported in freshwater and marine animals. The specific emphasis is on: (i) common cellular and molecular responses; (ii) stress proteins; (iii) redox homeostasis; (iv) cytoskeleton rearrangement; (v) metabolism reshuffle; (vi) free cellular energy and mitochondrial metabolism; and (vi) immunity. These endpoints are promising, notably in multi-biomarker approaches to identify precise cellular toxicity pathways and anticipate the impact of environmental metal pollution. |
| first_indexed | 2024-03-10T19:08:34Z |
| format | Article |
| id | doaj.art-cbf543834f6f47c99f7b4b16ff3cfed0 |
| institution | Directory Open Access Journal |
| issn | 2076-3298 |
| language | English |
| last_indexed | 2024-03-10T19:08:34Z |
| publishDate | 2020-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Environments |
| spelling | doaj.art-cbf543834f6f47c99f7b4b16ff3cfed02023-11-20T04:01:35ZengMDPI AGEnvironments2076-32982020-06-01764610.3390/environments7060046New Insights into Cellular Impacts of Metals in Aquatic AnimalsAimie Le Saux0Elise David1Stéphane Betoulle2Florence Bultelle3Béatrice Rocher4Iris Barjhoux5Claudia Cosio6Normandie Univ , UNIHAVRE, UMR I-02 SEBIO, FR CNRS 3730 SCALE, 76600 Le Havre, FranceUniversité de Reims Champagne Ardenne, URCA, UMR I-02 SEBIO, 51097 Reims, FranceUniversité de Reims Champagne Ardenne, URCA, UMR I-02 SEBIO, 51097 Reims, FranceNormandie Univ , UNIHAVRE, UMR I-02 SEBIO, FR CNRS 3730 SCALE, 76600 Le Havre, FranceNormandie Univ , UNIHAVRE, UMR I-02 SEBIO, FR CNRS 3730 SCALE, 76600 Le Havre, FranceUniversité de Reims Champagne Ardenne, URCA, UMR I-02 SEBIO, 51097 Reims, FranceUniversité de Reims Champagne Ardenne, URCA, UMR I-02 SEBIO, 51097 Reims, FranceToxic metals remain a current important threat to aquatic ecosystems, despite regulatory efforts to reduce their release. Several toxic metals already appear in the list of priority substances polluting surface waters, while concerns arise from the increasing use of technology-critical metals such as metallic nanoparticles, rare-earth, and platinum group metals. In aquatic environments, various chemical, biological and physical processes determine the impact of metals on the biota. This review provides insights into responses to toxic metals recently reported in freshwater and marine animals. The specific emphasis is on: (i) common cellular and molecular responses; (ii) stress proteins; (iii) redox homeostasis; (iv) cytoskeleton rearrangement; (v) metabolism reshuffle; (vi) free cellular energy and mitochondrial metabolism; and (vi) immunity. These endpoints are promising, notably in multi-biomarker approaches to identify precise cellular toxicity pathways and anticipate the impact of environmental metal pollution.https://www.mdpi.com/2076-3298/7/6/46bivalvecytoskeleton rearrangementfree cellular energy and mitochondrial metabolismmetabolism reshuffleredox homeostasisstress protein |
| spellingShingle | Aimie Le Saux Elise David Stéphane Betoulle Florence Bultelle Béatrice Rocher Iris Barjhoux Claudia Cosio New Insights into Cellular Impacts of Metals in Aquatic Animals Environments bivalve cytoskeleton rearrangement free cellular energy and mitochondrial metabolism metabolism reshuffle redox homeostasis stress protein |
| title | New Insights into Cellular Impacts of Metals in Aquatic Animals |
| title_full | New Insights into Cellular Impacts of Metals in Aquatic Animals |
| title_fullStr | New Insights into Cellular Impacts of Metals in Aquatic Animals |
| title_full_unstemmed | New Insights into Cellular Impacts of Metals in Aquatic Animals |
| title_short | New Insights into Cellular Impacts of Metals in Aquatic Animals |
| title_sort | new insights into cellular impacts of metals in aquatic animals |
| topic | bivalve cytoskeleton rearrangement free cellular energy and mitochondrial metabolism metabolism reshuffle redox homeostasis stress protein |
| url | https://www.mdpi.com/2076-3298/7/6/46 |
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