Canonical Wnt signaling induces focal adhesion and Integrin beta-1 endocytosis

Canonical Wnt signaling induces focal adhesion and Integrin beta-1 endocytosis

Summary: During canonical Wnt signaling, the Wnt receptor complex is sequestered together with glycogen synthase kinase 3 (GSK3) and Axin inside late endosomes, known as multivesicular bodies (MVBs). Here, we present experiments showing that Wnt causes the endocytosis of focal adhesion (FA) proteins...

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Bibliographic Details
Main Authors: Nydia Tejeda-Muñoz, Marco Morselli, Yuki Moriyama, Pooja Sheladiya, Matteo Pellegrini, Edward M. De Robertis
Format: Article
Language:English
Published: Elsevier 2022-04-01
Series:iScience
Subjects:
Cell biology
Developmental biology
Omics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222003935

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