Phytochemical screening and cytotoxic activity of a moss: Barbula javanica Dozy & Molk.

In the kingdom Plantae, bryophytes have the second-largest taxonomic group. These bryophytes are very limited and dispersed, so studies are conducted to understand their chemical composition. In this study, Total phenolic content (TPC), Total flavonoid content (TFC), Gas-chromatography and Mass spec...

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Main Authors: Swati Singh, Rimjhim Sharma, Bhavini Singh, Afroz Alam
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Results in Chemistry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211715623002424
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author Swati Singh
Rimjhim Sharma
Bhavini Singh
Afroz Alam
author_facet Swati Singh
Rimjhim Sharma
Bhavini Singh
Afroz Alam
author_sort Swati Singh
collection DOAJ
description In the kingdom Plantae, bryophytes have the second-largest taxonomic group. These bryophytes are very limited and dispersed, so studies are conducted to understand their chemical composition. In this study, Total phenolic content (TPC), Total flavonoid content (TFC), Gas-chromatography and Mass spectroscopy (GC–MS) analysis, and cytotoxic activities of different extracts from B. javanica have been tested. TPC and TFC showed higher yields in methanol than in n-hexane. It has also demonstrated six phytoconstituents in methanolic extracts, and cytotoxicity activity has been tested in which B. javanica depending on dose, had shown an antiproliferative effect on CRC cells. This present study reviews existing research and recommends additional studies to assess the cytotoxic effects of bryophytes.
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spelling doaj.art-cbfd3ae11e654eaeab7f4b11a715dfe82023-12-10T06:14:52ZengElsevierResults in Chemistry2211-71562023-12-016101003Phytochemical screening and cytotoxic activity of a moss: Barbula javanica Dozy & Molk.Swati Singh0Rimjhim Sharma1Bhavini Singh2Afroz Alam3Department of Bioscience and Biotechnology, Banasthali Vidyapith, Banasthali 304022, Rajasthan, IndiaDepartment of Bioscience and Biotechnology, Banasthali Vidyapith, Banasthali 304022, Rajasthan, IndiaFranklin College of Arts and Sciences, University of Georgia, Athens 30602, GA, United StatesDepartment of Bioscience and Biotechnology, Banasthali Vidyapith, Banasthali 304022, Rajasthan, India; Corresponding author.In the kingdom Plantae, bryophytes have the second-largest taxonomic group. These bryophytes are very limited and dispersed, so studies are conducted to understand their chemical composition. In this study, Total phenolic content (TPC), Total flavonoid content (TFC), Gas-chromatography and Mass spectroscopy (GC–MS) analysis, and cytotoxic activities of different extracts from B. javanica have been tested. TPC and TFC showed higher yields in methanol than in n-hexane. It has also demonstrated six phytoconstituents in methanolic extracts, and cytotoxicity activity has been tested in which B. javanica depending on dose, had shown an antiproliferative effect on CRC cells. This present study reviews existing research and recommends additional studies to assess the cytotoxic effects of bryophytes.http://www.sciencedirect.com/science/article/pii/S2211715623002424BryophytesMossPhenolGC–MS activityCytotoxicityXTT assay
spellingShingle Swati Singh
Rimjhim Sharma
Bhavini Singh
Afroz Alam
Phytochemical screening and cytotoxic activity of a moss: Barbula javanica Dozy & Molk.
Results in Chemistry
Bryophytes
Moss
Phenol
GC–MS activity
Cytotoxicity
XTT assay
title Phytochemical screening and cytotoxic activity of a moss: Barbula javanica Dozy & Molk.
title_full Phytochemical screening and cytotoxic activity of a moss: Barbula javanica Dozy & Molk.
title_fullStr Phytochemical screening and cytotoxic activity of a moss: Barbula javanica Dozy & Molk.
title_full_unstemmed Phytochemical screening and cytotoxic activity of a moss: Barbula javanica Dozy & Molk.
title_short Phytochemical screening and cytotoxic activity of a moss: Barbula javanica Dozy & Molk.
title_sort phytochemical screening and cytotoxic activity of a moss barbula javanica dozy amp molk
topic Bryophytes
Moss
Phenol
GC–MS activity
Cytotoxicity
XTT assay
url http://www.sciencedirect.com/science/article/pii/S2211715623002424
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