Trypanosoma cruzi: genetic structure of populations and relevance of genetic variability to the pathogenesis of chagas disease

Chagas disease, caused by the protozoan Trypanosoma cruzi, has a variable clinical course, ranging from symptomless infection to severe chronic disease with cardiovascular or gastrointestinal involvement or, occasionally, overwhelming acute episodes. The factors influencing this clinical variability...

Full description

Bibliographic Details
Main Authors: Andréa M Macedo, Carlos R Machado, Riva P Oliveira, Sérgio DJ Pena
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2004-02-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762004000100001