The natural FGF-trap long pentraxin 3 inhibits lymphangiogenesis and lymphatic dissemination

The natural FGF-trap long pentraxin 3 inhibits lymphangiogenesis and lymphatic dissemination

Abstract The lymphatic vascular system represents a major route for dissemination of several solid tumors, including melanoma. Even though the members of the Vascular Endothelial Growth Factor family VEGF-C and VEGF-A have been shown to drive tumor lymphangiogenesis, experimental evidence indicates...

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Bibliographic Details
Main Authors: Marta Turati, Arianna Giacomini, Sara Rezzola, Federica Maccarinelli, Giorgia Gazzaroli, Sonia Valentino, Barbara Bottazzi, Marco Presta, Roberto Ronca
Format: Article
Language:English
Published: BMC 2022-11-01
Series:Experimental Hematology & Oncology
Subjects:
Long pentraxin 3
Lymphangiogenesis
Fibroblast growth factor
Melanoma
Metastasis
Online Access:https://doi.org/10.1186/s40164-022-00330-w

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