Signal encoding in magnetic particle imaging: properties of the system function

<p>Abstract</p> <p>Background</p> <p>Magnetic particle imaging (MPI) is a new tomographic imaging technique capable of imaging magnetic tracer material at high temporal and spatial resolution. Image reconstruction requires solving a system of linear equations, which is...

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Main Authors: Gleich Bernhard, Weizenecker Jürgen, Rahmer Jürgen, Borgert Jörn
Format: Article
Language:English
Published: BMC 2009-04-01
Series:BMC Medical Imaging
Online Access:http://www.biomedcentral.com/1471-2342/9/4
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author Gleich Bernhard
Weizenecker Jürgen
Rahmer Jürgen
Borgert Jörn
author_facet Gleich Bernhard
Weizenecker Jürgen
Rahmer Jürgen
Borgert Jörn
author_sort Gleich Bernhard
collection DOAJ
description <p>Abstract</p> <p>Background</p> <p>Magnetic particle imaging (MPI) is a new tomographic imaging technique capable of imaging magnetic tracer material at high temporal and spatial resolution. Image reconstruction requires solving a system of linear equations, which is characterized by a "system function" that establishes the relation between spatial tracer position and frequency response. This paper for the first time reports on the structure and properties of the MPI system function.</p> <p>Methods</p> <p>An analytical derivation of the 1D MPI system function exhibits its explicit dependence on encoding field parameters and tracer properties. Simulations are used to derive properties of the 2D and 3D system function.</p> <p>Results</p> <p>It is found that for ideal tracer particles in a harmonic excitation field and constant selection field gradient, the 1D system function can be represented by Chebyshev polynomials of the second kind. Exact 1D image reconstruction can thus be performed using the Chebyshev transform. More realistic particle magnetization curves can be treated as a convolution of the derivative of the magnetization curve with the Chebyshev functions. For 2D and 3D imaging, it is found that Lissajous excitation trajectories lead to system functions that are closely related to tensor products of Chebyshev functions.</p> <p>Conclusion</p> <p>Since to date, the MPI system function has to be measured in time-consuming calibration scans, the additional information derived here can be used to reduce the amount of information to be acquired experimentally and can hence speed up system function acquisition. Furthermore, redundancies found in the system function can be removed to arrive at sparser representations that reduce memory load and allow faster image reconstruction.</p>
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spelling doaj.art-cc0284f293fd4f8bb4c75d03025655ba2022-12-22T03:24:50ZengBMCBMC Medical Imaging1471-23422009-04-0191410.1186/1471-2342-9-4Signal encoding in magnetic particle imaging: properties of the system functionGleich BernhardWeizenecker JürgenRahmer JürgenBorgert Jörn<p>Abstract</p> <p>Background</p> <p>Magnetic particle imaging (MPI) is a new tomographic imaging technique capable of imaging magnetic tracer material at high temporal and spatial resolution. Image reconstruction requires solving a system of linear equations, which is characterized by a "system function" that establishes the relation between spatial tracer position and frequency response. This paper for the first time reports on the structure and properties of the MPI system function.</p> <p>Methods</p> <p>An analytical derivation of the 1D MPI system function exhibits its explicit dependence on encoding field parameters and tracer properties. Simulations are used to derive properties of the 2D and 3D system function.</p> <p>Results</p> <p>It is found that for ideal tracer particles in a harmonic excitation field and constant selection field gradient, the 1D system function can be represented by Chebyshev polynomials of the second kind. Exact 1D image reconstruction can thus be performed using the Chebyshev transform. More realistic particle magnetization curves can be treated as a convolution of the derivative of the magnetization curve with the Chebyshev functions. For 2D and 3D imaging, it is found that Lissajous excitation trajectories lead to system functions that are closely related to tensor products of Chebyshev functions.</p> <p>Conclusion</p> <p>Since to date, the MPI system function has to be measured in time-consuming calibration scans, the additional information derived here can be used to reduce the amount of information to be acquired experimentally and can hence speed up system function acquisition. Furthermore, redundancies found in the system function can be removed to arrive at sparser representations that reduce memory load and allow faster image reconstruction.</p>http://www.biomedcentral.com/1471-2342/9/4
spellingShingle Gleich Bernhard
Weizenecker Jürgen
Rahmer Jürgen
Borgert Jörn
Signal encoding in magnetic particle imaging: properties of the system function
BMC Medical Imaging
title Signal encoding in magnetic particle imaging: properties of the system function
title_full Signal encoding in magnetic particle imaging: properties of the system function
title_fullStr Signal encoding in magnetic particle imaging: properties of the system function
title_full_unstemmed Signal encoding in magnetic particle imaging: properties of the system function
title_short Signal encoding in magnetic particle imaging: properties of the system function
title_sort signal encoding in magnetic particle imaging properties of the system function
url http://www.biomedcentral.com/1471-2342/9/4
work_keys_str_mv AT gleichbernhard signalencodinginmagneticparticleimagingpropertiesofthesystemfunction
AT weizeneckerjurgen signalencodinginmagneticparticleimagingpropertiesofthesystemfunction
AT rahmerjurgen signalencodinginmagneticparticleimagingpropertiesofthesystemfunction
AT borgertjorn signalencodinginmagneticparticleimagingpropertiesofthesystemfunction