Involvement of dopamine D2 receptors in addictive-like behaviour for acetaldehyde.

Acetaldehyde, the first metabolite of ethanol, is active in the central nervous system, where it exerts motivational properties. Acetaldehyde is able to induce drinking behaviour in operant-conflict paradigms that resemble the core features of the addictive phenotype: drug-intake acquisition and mai...

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Bibliographic Details
Main Authors: Anna Brancato, Fulvio Plescia, Rosa Anna Maria Marino, Giuseppe Maniaci, Michele Navarra, Carla Cannizzaro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4057173?pdf=render