The Antiviral Effect of the Chemical Compounds Targeting DED/EDh Motifs of the Viral Proteins on Lymphocytic Choriomeningitis Virus and SARS-CoV-2

The Antiviral Effect of the Chemical Compounds Targeting DED/EDh Motifs of the Viral Proteins on Lymphocytic Choriomeningitis Virus and SARS-CoV-2

Arenaviruses and coronaviruses include several human pathogenic viruses, such as Lassa virus, Lymphocytic choriomeningitis virus (LCMV), SARS-CoV, MERS-CoV, and SARS-CoV-2. Although these viruses belong to different virus families, they possess a common motif, the DED/EDh motif, known as an exonucle...

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Bibliographic Details
Main Authors: Mya Myat Ngwe Tun, Kouichi Morita, Takeshi Ishikawa, Shuzo Urata
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Viruses
Subjects:
Lymphocytic choriomeningitis virus (LCMV)
SARS-CoV-2
antivirals
exonuclease (ExoN) motif
DED/EDh motif
Online Access:https://www.mdpi.com/1999-4915/13/7/1220

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