The Role of TLR2 in Infection and Immunity
TLR2 forms heterodimers with TLR1 and 6 and these heterodimers are recognition molecules for a panoply of pathogens, allowing for significant innate immune responses that accounts for protection from these pathogens and immune sequelae related to infection with these pathogens. These pathogens incl...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2012-04-01
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| Series: | Frontiers in Immunology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00079/full |
| _version_ | 1818671825871175680 |
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| author | Laura ede Oliviera Nascimento Paola eMassari Lee Mark Wetzler |
| author_facet | Laura ede Oliviera Nascimento Paola eMassari Lee Mark Wetzler |
| author_sort | Laura ede Oliviera Nascimento |
| collection | DOAJ |
| description | TLR2 forms heterodimers with TLR1 and 6 and these heterodimers are recognition molecules for a panoply of pathogens, allowing for significant innate immune responses that accounts for protection from these pathogens and immune sequelae related to infection with these pathogens. These pathogens include bacteria, viruses, fungi and parasites. This review will discuss the current state of the art regarding TLR2 recognition of pathogen associated molecular patterns (PAMPS) and the relationship of the responses induced by such recognition to immune protection and pathology. |
| first_indexed | 2024-12-17T07:30:10Z |
| format | Article |
| id | doaj.art-cc0e26e6f23142888bcf511950d33a25 |
| institution | Directory Open Access Journal |
| issn | 1664-3224 |
| language | English |
| last_indexed | 2024-12-17T07:30:10Z |
| publishDate | 2012-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Immunology |
| spelling | doaj.art-cc0e26e6f23142888bcf511950d33a252022-12-21T21:58:30ZengFrontiers Media S.A.Frontiers in Immunology1664-32242012-04-01310.3389/fimmu.2012.0007920479The Role of TLR2 in Infection and ImmunityLaura ede Oliviera Nascimento0Paola eMassari1Lee Mark Wetzler2University of São PauloBoston University School of MedicineBoston University School of MedicineTLR2 forms heterodimers with TLR1 and 6 and these heterodimers are recognition molecules for a panoply of pathogens, allowing for significant innate immune responses that accounts for protection from these pathogens and immune sequelae related to infection with these pathogens. These pathogens include bacteria, viruses, fungi and parasites. This review will discuss the current state of the art regarding TLR2 recognition of pathogen associated molecular patterns (PAMPS) and the relationship of the responses induced by such recognition to immune protection and pathology.http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00079/fullBacteriaFungiImmunityInfectionInflammationViruses |
| spellingShingle | Laura ede Oliviera Nascimento Paola eMassari Lee Mark Wetzler The Role of TLR2 in Infection and Immunity Frontiers in Immunology Bacteria Fungi Immunity Infection Inflammation Viruses |
| title | The Role of TLR2 in Infection and Immunity |
| title_full | The Role of TLR2 in Infection and Immunity |
| title_fullStr | The Role of TLR2 in Infection and Immunity |
| title_full_unstemmed | The Role of TLR2 in Infection and Immunity |
| title_short | The Role of TLR2 in Infection and Immunity |
| title_sort | role of tlr2 in infection and immunity |
| topic | Bacteria Fungi Immunity Infection Inflammation Viruses |
| url | http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00079/full |
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