Clinical efficacy and bleeding outcomes of tissue plasminogen activator and dornase alfa in pleural space infection with once daily concurrent administration: a retrospective cohort study

Clinical efficacy and bleeding outcomes of tissue plasminogen activator and dornase alfa in pleural space infection with once daily concurrent administration: a retrospective cohort study

Abstract Objective The use of intrapleural tissue plasminogen activator (tPA) and dornase alfa (DNase) is common in the management of pleural space infection. We review our experience with the efficacy and safety of this therapy. We performed a single center, retrospective study of consecutive patie...

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Bibliographic Details
Main Authors: Chuan Jiang, Meng Xie, Kelly Cervellione, Craig Thurm
Format: Article
Language:English
Published: BMC 2020-08-01
Series:BMC Research Notes
Subjects:
Parapneumonic effusion
Empyema
Fibrinolytic therapy
Pleural disease
Online Access:http://link.springer.com/article/10.1186/s13104-020-05210-2

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