Thrombocytosis in children: Clinico-hematological profile from a single centre in Eastern India
BACKGROUND AND OBJECTIVE: Thrombocytosis is not an uncommon finding in hemograms of children with an incidence of 6%–15% among hospitalized children. This study aims to determine the etiology of thrombocytosis and analyze various platelet parameters in children attending our hospital. MAT...
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| Format: | Article |
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Thieme Medical and Scientific Publishers Pvt. Ltd.
2018-01-01
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| Series: | Journal of Laboratory Physicians |
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| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.4103/JLP.JLP_90_17 |
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| author | Rachita Sarangi Sarita Pradhan Avantika Dhanawat Rashmi Patanayak Gautam Benia |
| author_facet | Rachita Sarangi Sarita Pradhan Avantika Dhanawat Rashmi Patanayak Gautam Benia |
| author_sort | Rachita Sarangi |
| collection | DOAJ |
| description | BACKGROUND AND OBJECTIVE: Thrombocytosis is not an uncommon finding in hemograms of children with an incidence of 6%–15% among hospitalized children. This study aims to determine the etiology of thrombocytosis and analyze various platelet parameters in children attending our hospital.
MATERIALS AND METHODS: A prospective observational study was carried out in a tertiary care center in Odisha, in eastern part of India, for 6 months from July 2016 to December 2016. All children of age group 1–14 years of age attending pediatrics and other pediatric super specialty outdoors and/or admitted to indoors and whose complete blood counts (CBC) were done were included in the study. The CBC parameters such as hemoglobin, red blood cell indices, and platelet indices (platelet distribution width [PDW], mean platelet volume [MPV], platelet large cell ratio [P-LCR]) were noted.
RESULTS: Out of 2500 hemograms done in pediatrics age group, 272 (10.8%) patients showed thrombocytosis. About 99.6% of cases were of secondary thrombocytosis. Only one case of primary thrombocytosis was encountered. The most common cause of secondary thrombocytosis was infection (39.5%) alone followed by iron deficiency anemia (14.1%). With increasing platelet counts, a decrease in MPV, P-LCR, and PDW was noted which was statistically significant (P < 0.05).
CONCLUSION: Thrombocytosis is not rare (10.8%) in children. Secondary thrombocytosis is common and predominatly attributed to infection. |
| first_indexed | 2024-12-10T06:09:18Z |
| format | Article |
| id | doaj.art-cc128ddd7f6e49eeaccd49c2f92f7695 |
| institution | Directory Open Access Journal |
| issn | 0974-2727 0974-7826 |
| language | English |
| last_indexed | 2024-12-10T06:09:18Z |
| publishDate | 2018-01-01 |
| publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
| record_format | Article |
| series | Journal of Laboratory Physicians |
| spelling | doaj.art-cc128ddd7f6e49eeaccd49c2f92f76952022-12-22T01:59:36ZengThieme Medical and Scientific Publishers Pvt. Ltd.Journal of Laboratory Physicians0974-27270974-78262018-01-01100103403710.4103/JLP.JLP_90_17Thrombocytosis in children: Clinico-hematological profile from a single centre in Eastern IndiaRachita Sarangi0Sarita Pradhan1Avantika Dhanawat2Rashmi Patanayak3Gautam Benia4Department of Paediatrics, IMS and Sum Hospital, Bhubaneswar, Odisha, IndiaDepartment of Pathology, IMS and Sum Hospital, Bhubaneswar, Odisha, IndiaDepartment of Paediatrics, IMS and Sum Hospital, Bhubaneswar, Odisha, IndiaDepartment of Pathology, IMS and Sum Hospital, Bhubaneswar, Odisha, IndiaDepartment of Paediatrics, IMS and Sum Hospital, Bhubaneswar, Odisha, IndiaBACKGROUND AND OBJECTIVE: Thrombocytosis is not an uncommon finding in hemograms of children with an incidence of 6%–15% among hospitalized children. This study aims to determine the etiology of thrombocytosis and analyze various platelet parameters in children attending our hospital. MATERIALS AND METHODS: A prospective observational study was carried out in a tertiary care center in Odisha, in eastern part of India, for 6 months from July 2016 to December 2016. All children of age group 1–14 years of age attending pediatrics and other pediatric super specialty outdoors and/or admitted to indoors and whose complete blood counts (CBC) were done were included in the study. The CBC parameters such as hemoglobin, red blood cell indices, and platelet indices (platelet distribution width [PDW], mean platelet volume [MPV], platelet large cell ratio [P-LCR]) were noted. RESULTS: Out of 2500 hemograms done in pediatrics age group, 272 (10.8%) patients showed thrombocytosis. About 99.6% of cases were of secondary thrombocytosis. Only one case of primary thrombocytosis was encountered. The most common cause of secondary thrombocytosis was infection (39.5%) alone followed by iron deficiency anemia (14.1%). With increasing platelet counts, a decrease in MPV, P-LCR, and PDW was noted which was statistically significant (P < 0.05). CONCLUSION: Thrombocytosis is not rare (10.8%) in children. Secondary thrombocytosis is common and predominatly attributed to infection.http://www.thieme-connect.de/DOI/DOI?10.4103/JLP.JLP_90_17platelet indicesprimarysecondarythrombocytosis |
| spellingShingle | Rachita Sarangi Sarita Pradhan Avantika Dhanawat Rashmi Patanayak Gautam Benia Thrombocytosis in children: Clinico-hematological profile from a single centre in Eastern India Journal of Laboratory Physicians platelet indices primary secondary thrombocytosis |
| title | Thrombocytosis in children: Clinico-hematological profile from a single centre in Eastern India |
| title_full | Thrombocytosis in children: Clinico-hematological profile from a single centre in Eastern India |
| title_fullStr | Thrombocytosis in children: Clinico-hematological profile from a single centre in Eastern India |
| title_full_unstemmed | Thrombocytosis in children: Clinico-hematological profile from a single centre in Eastern India |
| title_short | Thrombocytosis in children: Clinico-hematological profile from a single centre in Eastern India |
| title_sort | thrombocytosis in children clinico hematological profile from a single centre in eastern india |
| topic | platelet indices primary secondary thrombocytosis |
| url | http://www.thieme-connect.de/DOI/DOI?10.4103/JLP.JLP_90_17 |
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