α-SNAP prevents docking of the acrosome during sperm exocytosis because it sequesters monomeric syntaxin.

α-SNAP prevents docking of the acrosome during sperm exocytosis because it sequesters monomeric syntaxin.

α-SNAP has an essential role in membrane fusion that consists of bridging cis SNARE complexes to NSF. α-SNAP stimulates NSF, which releases itself, α-SNAP, and individual SNAREs that subsequently re-engage in the trans arrays indispensable for fusion. α-SNAP also binds monomeric syntaxin and NSF dis...

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Bibliographic Details
Main Authors: Facundo Rodríguez, Matías A Bustos, María N Zanetti, María C Ruete, Luis S Mayorga, Claudia N Tomes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3138754?pdf=render

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