Uncoupling protein-1 as a target for the treatment of obesity/insulin resistance

Uncoupling protein-1 as a target for the treatment of obesity/insulin resistance

Presence of brown adipose tissue (BAT), characterised by the expression of the thermogenic uncoupling protein 1 (UCP1), has recently been described in adult humans. UCP1 is expressed in classical brown adipocytes, as well as in beige cells in white adipose tissue (WAT). The thermogenic activity of B...

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Bibliographic Details
Main Authors: Anne-Laure ePoher, Jordi eAltirriba, Christelle eVeyrat-Durebex, Françoise eROHNER-JEANRENAUD
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-01-01
Series:Frontiers in Physiology
Subjects:
Obesity
diabetes
Pten
BMP
IL-6
UCP1
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2015.00004/full

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