Anti-Cancer Activity of As<sub>4</sub>O<sub>6</sub> and its Efficacy in a Series of Patient-Derived Xenografts for Human Cervical Cancer
Purpose: To investigate the anti-cancer effects of tetraarsenic hexoxide (TAO, As<sub>4</sub>O<sub>6</sub>) in cervical cancer cell lines and in a series of patient-derived xenograft (PDX) mouse models. Methods: Human cervical cancer cell lines, including HeLa, SiHa and CaSki...
Main Authors: | Joseph J. Noh, Myeong-Seon Kim, Young-Jae Cho, Soo-Young Jeong, Yoo-Young Lee, Ji-Yoon Ryu, Jung-Joo Choi, Illju Bae, Zhaoyan Wu, Byoung-Gie Kim, Jae Ryoung Hwang, Jeong-Won Lee |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-10-01
|
Series: | Pharmaceutics |
Subjects: | |
Online Access: | https://www.mdpi.com/1999-4923/12/10/987 |
Similar Items
-
Impact of the Pd<sub>2</sub>Spm (Spermine) Complex on the Metabolism of Triple-Negative Breast Cancer Tumors of a Xenograft Mouse Model
by: Tatiana J. Carneiro, et al.
Published: (2021-10-01) -
Pd<sub>2</sub>Spermine Complex Shows Cancer Selectivity and Efficacy to Inhibit Growth of Triple-Negative Breast Tumors in Mice
by: Martin Vojtek, et al.
Published: (2022-01-01) -
Tetraarsenic tetrasulfide triggers ROS-induced apoptosis and ferroptosis in B-cell acute lymphoblastic leukaemia by targeting HK2
by: Wenke Bai, et al.
Published: (2024-02-01) -
Factors associated with engraftment success of patient-derived xenografts of breast cancer
by: Jongwon Lee, et al.
Published: (2024-03-01) -
Preclinical Therapeutic Assessment of a New Chemotherapeutics [Dichloro(4,4’-Bis(2,2,3,3-Tetrafluoropropoxy) Methyl)-2,2’-Bipryridine) Platinum] in an Orthotopic Patient-Derived Xenograft Model of Triple-Negative Breast Cancers
by: Tzu-Chun Kan, et al.
Published: (2022-04-01)